HitPredict

Interactor 1: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35709258
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1030 Hs			1 703
+	Hs
		161319 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		148138 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		161423 MYPT1_HUMAN (1-1030): 4.91e-140: 448: 100.00		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Hs
		1206031 MIB1_HUMAN (41-304): 3.48e-51: 198: 21.75		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		862098 DAPK1_HUMAN (43-515): 3.48e-54: 208: 15.55		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		1206041 MIB1_HUMAN (41-304): 3.48e-51: 198: 21.75		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		225128 MYPT2_HUMAN (1-905): 6.08e-21: 101: 11.37		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Dm
		1303397 Q9VJ14_DROME (140-612): 6.22e-24: 111: 14.07		MYSN_DROME (1-430): 3.81e-15: 82.1: 12.70
+	Mm
		57429 A2AM57_MOUSE (152-919): 6.73e-16: 84.9: 8.55		MYH9_MOUSE (1-520): 1.09e-21: 102: 11.22
+	Mm
		57397 A2AM57_MOUSE (152-919): 6.73e-16: 84.9: 8.55		Q3UFT0_MOUSE (201-702): 3.37e-21: 100: 11.64
+	Hs
		225152 MYPT2_HUMAN (1-905): 6.08e-21: 101: 11.37		MY18A_HUMAN (51-572): 5.91e-15: 81.2: 16.15
+	Mm
		57340 A2AM57_MOUSE (152-919): 6.73e-16: 84.9: 8.55		DESP_MOUSE (59-550): 4.18e-09: 62.5: 18.91