HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: PAXI (P49023)
Paxillin
Gene: PXN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.563

Property	Details
Experiments	26673895, 22833565
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 591
+	Hs
		162223 XPO1_HUMAN (1-1071): 0: 1022: 100.00		TGFI1_HUMAN (1-532): 4.62e-63: 216: 24.91
+	Hs
		163331 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PDLI7_HUMAN (473-590): 2.88e-34: 137: 33.90
+	Hs
		163089 XPO1_HUMAN (1-1071): 0: 1022: 100.00		LPP_HUMAN (472-590): 5.36e-23: 105: 26.23
+	Hs
		163420 XPO1_HUMAN (1-1071): 0: 1022: 100.00		LIMD1_HUMAN (467-588): 1.05e-22: 104: 22.48
+	Xl
		1119808 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q52L12_XENLA (468-590): 2.66e-24: 109: 25.40
+	Hs
		163141 XPO1_HUMAN (1-1071): 0: 1022: 100.00		PDLI5_HUMAN (530-590): 3.57e-11: 68: 34.43
+	Hs
		150491 XPO1_HUMAN (1-1071): 0: 1022: 100.00		ABLM1_HUMAN (512-590): 6.08e-10: 64.4: 25.32
+	Xl
		1103293 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		TGFI1_XENLA (344-414): 2.2e-13: 74.6: 36.62
+	Hs
		297199 IPO13_HUMAN (17-1029): 3.79e-133: 429: 16.03		PDLI7_HUMAN (473-590): 2.88e-34: 137: 33.90
+	Hs
		155648 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		PDLI7_HUMAN (473-590): 2.88e-34: 137: 33.90
+	Hs
		1158944 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		ZFP1_HUMAN (236-414): 3.69e-22: 101: 7.18
+	Hs
		1060787 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		ZFP1_HUMAN (236-414): 3.69e-22: 101: 7.18