HitPredict

Interactor 1: AT2A1 (O14983)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A1

Interactor 2: CCR8 (P51685)
C-C chemokine receptor type 8 (C-C CKR-8) (CC-CKR-8) (CCR-8) (CC chemokine receptor CHEMR1) (CMKBRL2) (Chemokine receptor-like 1) (CKR-L1) (GPR-CY6) (GPRCY6) (TER1) (CD antigen CDw198)
Gene: CCR8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1001 Hs			1 355
+	Hs
		1031036 AT2A3_HUMAN (1-999): 0: 950: 75.88		GPR17_HUMAN (36-343): 1.5e-83: 259: 27.48
+	Hs
		561566 AT2A2_HUMAN (1-1000): 0: 950: 83.40		GPR17_HUMAN (36-343): 1.5e-83: 259: 27.48
+	Hs
		561533 AT2A2_HUMAN (1-1000): 0: 950: 83.40		CCR4_HUMAN (2-355): 9.67e-77: 242: 43.10
+	Hs
		561517 AT2A2_HUMAN (1-1000): 0: 950: 83.40		OPRD_HUMAN (19-345): 1.13e-70: 226: 25.00
+	Hs
		849697 AT2A3_HUMAN (1-999): 0: 950: 75.88		CCR6_HUMAN (2-328): 1.26e-70: 226: 33.13
+	Hs
		428908 AT2A2_HUMAN (1-1000): 0: 950: 83.40		ADRB2_HUMAN (8-339): 6.49e-68: 220: 15.18
+	Hs
		530883 AT1A3_HUMAN (2-998): 0: 800: 26.20		GPR17_HUMAN (36-343): 1.5e-83: 259: 27.48
+	Hs
		530862 AT1A3_HUMAN (2-998): 0: 800: 26.20		CXCR4_HUMAN (3-332): 1.63e-71: 228: 31.72
+	Hs
		392982 AT1A1_HUMAN (2-998): 0: 803: 26.10		ADRB2_HUMAN (8-339): 6.49e-68: 220: 15.18
+	Hs
		619229 AT2B4_HUMAN (5-993): 0: 761: 25.05		GPR17_HUMAN (36-343): 1.5e-83: 259: 27.48
+	Hs
		530844 AT1A3_HUMAN (2-998): 0: 800: 26.20		OPRX_HUMAN (10-344): 3.37e-67: 217: 24.71
+	Hs
		134361 AT2B4_HUMAN (5-993): 0: 761: 25.05		ACKR2_HUMAN (10-315): 1.56e-81: 255: 36.33
+	Hs
		895636 AT2B3_HUMAN (3-993): 0: 767: 24.31		CXCR4_HUMAN (3-332): 1.63e-71: 228: 31.72
+	Hs
		674851 AT2B3_HUMAN (3-993): 0: 767: 24.31		AGTR1_HUMAN (24-353): 8.23e-69: 221: 27.73
+	Hs
		619214 AT2B4_HUMAN (5-993): 0: 761: 25.05		CCR6_HUMAN (2-328): 1.26e-70: 226: 33.13
+	Hs
		619204 AT2B4_HUMAN (5-993): 0: 761: 25.05		APJ_HUMAN (13-350): 3.05e-69: 223: 24.23
+	Hs
		781059 AT2B3_HUMAN (3-993): 0: 767: 24.31		OPRX_HUMAN (10-344): 3.37e-67: 217: 24.71
+	Hs
		619202 AT2B4_HUMAN (5-993): 0: 761: 25.05		AGTR1_HUMAN (24-353): 8.23e-69: 221: 27.73
+	Hs
		428921 AT2B4_HUMAN (5-993): 0: 761: 25.05		ADRB2_HUMAN (8-339): 6.49e-68: 220: 15.18
+	Hs
		619206 AT2B4_HUMAN (5-993): 0: 761: 25.05		OPRX_HUMAN (10-344): 3.37e-67: 217: 24.71