Protein: URN1
Pre-mRNA-splicing factor URN1 (U2-U5-U6 snRNP, RES complex and NTC-interacting pre-mRNA-splicing factor 1)

Gene: URN1
Organism: Saccharomyces cerevisiae S288C
Interactions: 232
UniProt ID: Q06525

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005685 - U1 snRNP
GO:0045292 - mRNA cis splicing, via spliceosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672078

BUD31
Pre-mRNA-splicing factor BUD31

2

0

High-throughput

0.728

High

739208

PRP19
Pre-mRNA-processing factor 19

2

0

High-throughput

0.633

High

1055560

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.586

High

527770

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.585

High

744170

BRR2
Pre-mRNA-splicing helicase BRR2

2

0

High-throughput

0.576

High

569868

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.569

High

1031057

NOP3
Serine/arginine

2

0

High-throughput

0.569

High

727337

HS104
Heat shock protein 104

2

0

High-throughput

0.547

High

368063

ENO2
Enolase 2

2

1

High-throughput

0.543

High

1055573

CLF1
Pre-mRNA-splicing factor CLF1

1

1

High-throughput

0.536

High

893234

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

2

2

High-throughput

0.521

High

700154

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.513

High

751794

PRP8
Pre-mRNA-splicing factor 8

1

0

High-throughput

0.513

High

780228

SN114
Pre-mRNA-splicing factor SNU114

1

0

High-throughput

0.513

High

817168

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

0

High-throughput

0.513

High

892790

SF3B1
U2 snRNP component HSH155

1

0

High-throughput

0.513

High

1037757

CUS1
Cold sensitive U2 snRNA suppressor 1

1

0

High-throughput

0.513

High

1043509

CEF1
Pre-mRNA-splicing factor CEF1

1

0

High-throughput

0.513

High

1047387

RSE1
Pre-mRNA-splicing factor RSE1

1

0

High-throughput

0.513

High

1053561

SN309
Pre-mRNA-splicing factor SNT309

1

0

High-throughput

0.513

High

1054383

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

1055566

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.513

High

1055575

PRP46
Pre-mRNA-splicing factor PRP46

1

0

High-throughput

0.513

High

656634

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

656885

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

748902

SWE1
Mitosis inhibitor protein kinase SWE1

1

1

High-throughput

0.501

High

818700

GPP2
Glycerol-1-phosphate phosphohydrolase 2

1

1

High-throughput

0.501

High

602145

SPO12
Sporulation-specific protein 12

1

0

Small-scale

0.486

High

366841

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.480

High

441264

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

578253

TAL1
Transaldolase

1

0

High-throughput

0.480

High

628234

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

0

High-throughput

0.480

High

728718

ACBP
Acyl-CoA-binding protein

1

0

High-throughput

0.480

High

757638

SIP2
SNF1 protein kinase subunit beta-2

1

0

High-throughput

0.480

High

809419

STM1
Suppressor protein STM1

1

0

High-throughput

0.480

High

813395

NPT1
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.480

High

865945

YJ66
Uncharacterized oxidoreductase YJR096W

1

0

High-throughput

0.480

High

887766

RIR4
Ribonucleoside-diphosphate reductase small chain 2

1

0

High-throughput

0.480

High

923791

GOR1
Glyoxylate reductase 1

1

0

High-throughput

0.480

High

1053181

KYNU
Kynureninase

1

0

High-throughput

0.480

High

1055565

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.480

High

1055572

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.480

High

409789

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.479

High

436527

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.479

High

509927

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

2

High-throughput

0.479

High

637288

PWP1
Periodic tryptophan protein 1

1

1

High-throughput

0.479

High

663727

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.479

High

742957

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.479

High

751010

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

High-throughput

0.479

High

793535

MAK5
ATP-dependent RNA helicase MAK5

1

1

High-throughput

0.479

High

815245

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

816911

NUG1
Nuclear GTP-binding protein NUG1

1

1

High-throughput

0.479

High

834727

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

1

High-throughput

0.479

High

1044469

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

1046045

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

1055576

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

1055577

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

382367

H4
Histone H4

1

0

High-throughput

0.458

High

383366

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.458

High

402122

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

438496

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.458

High

439433

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

449014

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

454006

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.458

High

486792

CDC16
Anaphase-promoting complex subunit CDC16

1

0

High-throughput

0.458

High

553564

PDR1
Transcription factor PDR1

1

0

High-throughput

0.458

High

564681

STE12
Protein STE12

1

0

High-throughput

0.458

High

585388

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

586030

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.458

High

625135

PRP9
Pre-mRNA-splicing factor PRP9

1

0

High-throughput

0.458

High

626542

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.458

High

638820

REB1
DNA-binding protein REB1

1

0

High-throughput

0.458

High

664352

SSD1
Protein SSD1

1

0

High-throughput

0.458

High

666550

DBP2
ATP-dependent RNA helicase DBP2

1

0

High-throughput

0.458

High

672783

SNT1
Probable DNA-binding protein SNT1

1

0

High-throughput

0.458

High

678746

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

0

High-throughput

0.458

High

680089

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

684853

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

694652

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.458

High

708276

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

710000

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

739096

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

0

High-throughput

0.458

High

743055

SWI3
SWI/SNF complex subunit SWI3

1

0

High-throughput

0.458

High

750900

PRS6B
26S proteasome regulatory subunit 6B homolog

1

0

High-throughput

0.458

High

776655

DEF1
RNA polymerase II degradation factor 1

1

0

High-throughput

0.458

High

779107

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.458

High

781809

SET3
SET domain-containing protein 3

1

0

High-throughput

0.458

High

797694

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

805223

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

0

High-throughput

0.458

High

805641

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

813659

NUP60
Nucleoporin NUP60

1

0

High-throughput

0.458

High

813722

ECM1
Shuttling pre-60S factor ECM1

1

0

High-throughput

0.458

High

816672

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

821041

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

0

High-throughput

0.458

High

836538

T2FA
Transcription initiation factor IIF subunit alpha

1

0

High-throughput

0.458

High

836557

T2FB
Transcription initiation factor IIF subunit beta

1

0

High-throughput

0.458

High

843180

PFS2
Polyadenylation factor subunit 2

1

0

High-throughput

0.458

High

858362

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.458

High

858422

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.458

High

864191

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.458

High

893416

PSP2
Protein PSP2

1

0

High-throughput

0.458

High

918834

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

924377

APC1
Anaphase-promoting complex subunit 1

1

0

High-throughput

0.458

High

1028613

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1030581

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.458

High

1036961

ABF2
ARS-binding factor 2, mitochondrial

1

0

High-throughput

0.458

High

1043597

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.458

High

1049105

YM94
Uncharacterized protein YMR315W

1

0

High-throughput

0.458

High

1050174

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

1051565

RT103
Regulator of Ty1 transposition protein 103

1

0

High-throughput

0.458

High

1055567

NEW1
[NU+] prion formation protein 1

1

0

High-throughput

0.458

High

1055568

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

1055579

HSH49
Protein HSH49

1

0

High-throughput

0.458

High

676877

YCC1
Putative uncharacterized protein YCL021W

1

1

High-throughput

0.457

High

692437

KCC1
Calcium/calmodulin-dependent protein kinase I

1

1

High-throughput

0.457

High

789794

ADCS
Aminodeoxychorismate synthase

1

1

High-throughput

0.457

High

1055574

PMG3
Phosphoglycerate mutase 3

1

1

High-throughput

0.457

High

525258

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

742476

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

367127

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.437

High

367814

ENO1
Enolase 1

1

1

High-throughput

0.437

High

368761

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.437

High

430929

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

1

High-throughput

0.437

High

592517

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.437

High

598921

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

1

1

High-throughput

0.437

High

599079

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

1

High-throughput

0.437

High

603553

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.437

High

649676

KCC2
Calcium/calmodulin-dependent protein kinase II

1

1

High-throughput

0.437

High

745143

YME1
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1

1

1

High-throughput

0.437

High

802115

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.437

High

815336

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

1

High-throughput

0.437

High

825337

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

1

High-throughput

0.437

High

871512

ASK10
Activator of SKN7 protein 10

1

1

High-throughput

0.437

High

893166

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

2

High-throughput

0.437

High

917693

LSG1
Large subunit GTPase 1

1

1

High-throughput

0.437

High

918699

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.437

High

1028032

ACAC
Acetyl-CoA carboxylase

1

1

High-throughput

0.437

High

1055569

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.437

High

1055578

NOP58
Nucleolar protein 58

1

1

High-throughput

0.437

High

546405

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

1036180

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.426

High

509730

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.408

High

737499

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.407

High

797796

AIM4
Altered inheritance of mitochondria protein 4

5

0

High-throughput

0.376

High

1030257

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

2

0

High-throughput

0.310

High

453804

PYR1
Multifunctional protein URA2

2

0

High-throughput

0.298

High

150105

YL202
Putative uncharacterized protein YLR202C

1

0

High-throughput

0.261

Low

442126

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.261

Low

446249

PHSG
Glycogen phosphorylase

1

0

High-throughput

0.261

Low

449186

CALM
Calmodulin

1

0

High-throughput

0.261

Low

534197

PCKA
Phosphoenolpyruvate carboxykinase

1

0

High-throughput

0.261

Low

582255

AMPD
AMP deaminase

1

0

High-throughput

0.261

Low

655601

TKT1
Transketolase 1

1

0

High-throughput

0.261

Low

668441

PTP1
Tyrosine-protein phosphatase 1

1

0

High-throughput

0.261

Low

723633

MLS1
Malate synthase 1

1

0

High-throughput

0.261

Low

736140

ARP2
Actin-related protein 2

1

0

High-throughput

0.261

Low

763770

THI80
Thiamine pyrophosphokinase

1

0

High-throughput

0.261

Low

782049

YK27
Putative uncharacterized protein YKR047W

1

0

High-throughput

0.261

Low

791988

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.261

Low

793231

YBQ6
Uncharacterized glycosyl hydrolase YBR056W

1

0

High-throughput

0.261

Low

798049

YB76
Putative uncharacterized protein YBR226C

1

0

High-throughput

0.261

Low

802976

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.261

Low

803498

TDA3
Putative oxidoreductase TDA3

1

0

High-throughput

0.261

Low

825431

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.261

Low

864716

YJC2
Putative uncharacterized protein YJL009W

1

0

High-throughput

0.261

Low

916837

MALX3
Oligo-1,6-glucosidase IMA1

1

0

High-throughput

0.261

Low

917022

YGV4
Uncharacterized protein YGL204C

1

0

High-throughput

0.261

Low

924090

YNW6
Putative uncharacterized protein YNL226W

1

0

High-throughput

0.261

Low

1009784

PURA
Adenylosuccinate synthetase

1

0

High-throughput

0.261

Low

1018187

YD271
Putative uncharacterized protein YDR271C

1

0

High-throughput

0.261

Low

1044007

ENT5
Epsin-5

1

0

Small-scale

0.261

Low

1052204

EIF3J
Eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.261

Low

1054938

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.261

Low

1055571

YD061
Uncharacterized ABC transporter ATP-binding protein YDR061W

1

0

High-throughput

0.261

Low

358345

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.249

Low

365698

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.249

Low

366729

HIS2
Histidine biosynthesis trifunctional protein [Includes: Phosphoribosyl-AMP cyclohydrolase

1

0

High-throughput

0.249

Low

368486

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.249

Low

435635

RS9B
Small ribosomal subunit protein uS4B

1

0

High-throughput

0.249

Low

450649

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.249

Low

475142

CYAA
Adenylate cyclase

1

0

High-throughput

0.249

Low

478644

IF2B
Eukaryotic translation initiation factor 2 subunit beta

1

0

High-throughput

0.249

Low

511700

RS23B
Small ribosomal subunit protein uS12B

1

0

High-throughput

0.249

Low

513238

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514851

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

531408

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.249

Low

572652

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.249

Low

580119

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

585571

BGL2
Glucan 1,3-beta-glucosidase

1

0

High-throughput

0.249

Low

605350

CAP
Adenylyl cyclase-associated protein

1

0

High-throughput

0.249

Low

613639

ADT2
ADP,ATP carrier protein 2

1

0

High-throughput

0.249

Low

618624

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.249

Low

672353

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.249

Low

678130

SYP1
Suppressor of yeast profilin deletion

1

0

High-throughput

0.249

Low

698157

KRE2
Glycolipid 2-alpha-mannosyltransferase

1

0

High-throughput

0.249

Low

727688

TPS2
Trehalose-phosphatase

1

0

High-throughput

0.249

Low

751123

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

0

High-throughput

0.249

Low

751493

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.249

Low

763500

MDJ1
DnaJ homolog 1, mitochondrial

1

0

High-throughput

0.249

Low

796632

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

0

High-throughput

0.249

Low

801110

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.249

Low

802404

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

802699

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.249

Low

814047

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.249

Low

829852

PHB1
Prohibitin-1

1

0

High-throughput

0.249

Low

836341

BNI1
Protein BNI1

1

0

High-throughput

0.249

Low

858135

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.249

Low

864334

NET1
Nucleolar protein NET1

1

0

High-throughput

0.249

Low

868450

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.249

Low

871859

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.249

Low

902677

RL9B
Large ribosomal subunit protein uL6B

1

0

High-throughput

0.249

Low

917635

MLC1
Myosin light chain 1

1

0

High-throughput

0.249

Low

917832

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

919263

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.249

Low

1033457

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.249

Low

1035280

OSH6
Oxysterol-binding protein homolog 6

1

0

High-throughput

0.249

Low

1035298

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.249

Low

1039144

MUK1
Protein MUK1

1

0

High-throughput

0.249

Low

1040696

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.249

Low

1043473

TCB3
Tricalbin-3

1

0

High-throughput

0.249

Low

1049970

IVY1
Protein IVY1

1

0

High-throughput

0.249

Low

1054955

RGA2
Rho-type GTPase-activating protein 2

1

0

High-throughput

0.249

Low

1055561

BFR2
Protein BFR2

1

0

High-throughput

0.249

Low

1055562

NVJ2
Nucleus-vacuole junction protein 2

1

0

High-throughput

0.249

Low

1055563

PUF3
mRNA-binding protein PUF3

1

0

High-throughput

0.249

Low

1055564

LAM6
Membrane-anchored lipid-binding protein LAM6

1

0

High-throughput

0.249

Low

1055570

HER1
HMG2-induced ER-remodeling protein 1

1

0

High-throughput

0.249

Low

394930

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

510843

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

863756

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

825861

YIG0
Uncharacterized protein YIL060W

1

0

High-throughput

0.213

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025