HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: LAMP2 (P13473)
Lysosome-associated membrane glycoprotein 2 (LAMP-2) (Lysosome-associated membrane protein 2) (CD107 antigen-like family member B) (LGP-96) (CD antigen CD107b)
Gene: LAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005886 - plasma membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2390 Hs			1 410
+	Hs
		527398 SPTB2_HUMAN (3-2390): 0: 712: 61.09		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		164559 SPTN2_HUMAN (1-2390): 0: 715: 100.00		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		506971 SPTB2_HUMAN (3-2390): 0: 712: 61.09		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		164676 SPTN2_HUMAN (1-2390): 0: 715: 100.00		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		963452 SPTB2_HUMAN (3-2390): 0: 712: 61.09		LAMP3_HUMAN (155-410): 7.26e-75: 240: 25.95
+	Hs
		3526 A0A0U1RQJ2_HUMAN (345-2154): 2.53e-86: 318: 14.85		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		507009 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43
+	Hs
		527408 DYST_HUMAN (1807-2150): 4.68e-11: 71: 13.35		LAMP2_HUMAN (1-410): 0: 557: 100.00
+	Hs
		506977 DYST_HUMAN (1807-2150): 4.68e-11: 71: 13.35		LAMP1_HUMAN (26-410): 3.76e-155: 446: 34.43