HitPredict

Interactor 1: SC16A (O15027)
Protein transport protein Sec16A (SEC16 homolog A) (p250)
Gene: SEC16A

Interactor 2: SC23B (Q15437)
Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)
Gene: SEC23B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26496610, 30596474, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm GO:0070971 - endoplasmic reticulum exit site
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2357 Hs			1 767
+	Hs
		164901 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		99722 SC16A_HUMAN (1-2357): 0: 820: 100.00		F5H365_HUMAN (1-766): 0: 1000: 81.85
+	Hs
		164730 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC24B_HUMAN (6-754): 0: 591: 18.75
+	Hs
		164840 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC24C_HUMAN (2-721): 0: 570: 16.67
+	Hs
		164729 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC24A_HUMAN (4-760): 0: 559: 19.20
+	Hs
		164725 SC16A_HUMAN (1-2357): 0: 820: 100.00		SC24D_HUMAN (9-680): 0: 557: 16.78
+	Hs
		302290 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		867101 SC24C_HUMAN (716-1040): 9.25e-09: 63.3: 17.02		SC23B_HUMAN (1-767): 0: 1075: 100.00
+	Hs
		302289 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Hs
		867100 SC24C_HUMAN (716-1040): 9.25e-09: 63.3: 17.02		SC23A_HUMAN (1-766): 0: 1050: 84.73
+	Ce
		712437 SC161_CAEEL (1432-2256): 2.55e-38: 160: 20.26		Q9U2Z1_CAEEL (1-757): 0: 902: 55.72
+	Sc
		546759 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		SEC23_YEAST (9-764): 0: 860: 49.94
+	Sc
		546735 SEC31_YEAST (5-336): 7.22e-09: 63.4: 12.47		SEC23_YEAST (9-764): 0: 860: 49.94
+	Ce
		712430 SC161_CAEEL (1432-2256): 2.55e-38: 160: 20.26		Q23368_CAEEL (13-760): 4.14e-179: 540: 17.58
+	Sc
		817592 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		SFB2_YEAST (16-663): 6.52e-170: 513: 14.54
+	Sc
		774421 SEC16_YEAST (835-2347): 2.61e-42: 174: 13.25		SEC24_YEAST (10-663): 1.02e-168: 511: 15.04
+	Hs
		302269 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		SC24C_HUMAN (2-721): 0: 570: 16.67
+	Hs
		297843 SC31A_HUMAN (26-347): 7.63e-09: 63.5: 12.31		SC24D_HUMAN (9-680): 0: 557: 16.78
+	Sc
		758535 SEC31_YEAST (5-336): 7.22e-09: 63.4: 12.47		SEC24_YEAST (10-663): 1.02e-168: 511: 15.04