Protein: TNR16
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (Low-affinity nerve growth factor receptor p75NGFR) (Low-affinity nerve growth factor receptor p75NGR) (p75 ICD) (CD antigen CD271)

Gene: TNR16, NGFR
Organism: Homo sapiens
Interactions: 67
UniProt ID: P08138

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001678 - intracellular glucose homeostasis
GO:0004888 - transmembrane signaling receptor activity
GO:0005035 - death receptor activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

376943

NGF
Beta-nerve growth factor

6

1

Small-scale

0.951

High

421333

A4
Amyloid-beta precursor protein

4

4

Small-scale

0.902

High

466556

TNR16
Tumor necrosis factor receptor superfamily member 16

3

15

Small-scale

0.834

High

466566

IRAK1
Interleukin-1 receptor-associated kinase 1

2

1

Small-scale

0.754

High

466564

CD80
T-lymphocyte activation antigen CD80

1

5

Small-scale

0.747

High

284499

TNR21
Tumor necrosis factor receptor superfamily member 21

1

17

Small-scale

0.724

High

466604

TRAF6
TNF receptor-associated factor 6

4

20

Small-scale

0.692

High

411208

NTRK1
High affinity nerve growth factor receptor

4

13

Small-scale

0.679

High

466592

NECD
Necdin

3

9

Small-scale

0.664

High

466574

SQSTM
Sequestosome-1

3

4

Small-scale

0.640

High

466587

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

3

2

Small-scale

0.640

High

466591

SORT
Sortilin

3

8

Small-scale

0.640

High

466594

TRAF4
TNF receptor-associated factor 4

2

20

Small-scale

0.629

High

214375

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

10

Small-scale

0.618

High

466561

NTF3
Neurotrophin-3

1

1

Small-scale

0.618

High

466578

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

10

Small-scale

0.618

High

466593

MYD88
Myeloid differentiation primary response protein MyD88

1

1

Small-scale

0.618

High

466599

KDIS
Kinase D-interacting substrate of 220 kDa

1

4

Small-scale

0.618

High

167794

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

2

17

Small-scale

0.584

High

466595

RTN4R
Reticulon-4 receptor

2

6

Small-scale

0.584

High

466605

MAGD1
Melanoma-associated antigen D1

2

7

Small-scale

0.584

High

466562

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

4

Small-scale

0.573

High

466588

NSE3
Non-structural maintenance of chromosomes element 3 homolog

1

7

Small-scale

0.573

High

466598

BFAR
Bifunctional apoptosis regulator

1

5

Small-scale

0.573

High

466596

MAGH1
Melanoma-associated antigen H1

2

9

Small-scale

0.570

High

413035

P53
Cellular tumor antigen p53

1

4

Small-scale

0.561

High

466571

TRAF2
TNF receptor-associated factor 2

1

20

Small-scale

0.561

High

239350

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

Small-scale

0.549

High

466581

FSCN1
Fascin

1

0

Small-scale

0.549

High

466568

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.537

High

466575

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

7

High-throughput

0.536

High

466590

SCN2A
Sodium channel protein type 2 subunit alpha

1

2

High-throughput

0.536

High

466603

SALL2
Sal-like protein 2

1

7

Small-scale

0.535

High

466582

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

4

High-throughput

0.515

High

466600

CHIP
E3 ubiquitin-protein ligase CHIP

1

14

High-throughput

0.515

High

123211

PDLI1
PDZ and LIM domain protein 1

1

1

Small-scale

0.512

High

405379

KITH
Thymidine kinase, cytosolic

1

1

High-throughput

0.508

High

466557

H2AX
Histone H2AX

1

1

High-throughput

0.508

High

466560

ANXA7
Annexin A7

1

3

High-throughput

0.508

High

466580

SMN
Survival motor neuron protein

1

1

High-throughput

0.508

High

466586

STMN2
Stathmin-2

1

1

High-throughput

0.508

High

323113

TRI37
E3 ubiquitin-protein ligase TRIM37

1

9

Small-scale

0.501

High

466558

EGR1
Early growth response protein 1

1

9

Small-scale

0.501

High

466570

CAV1
Caveolin-1

1

4

Small-scale

0.501

High

466589

SORC2
VPS10 domain-containing receptor SorCS2 [Cleaved into: SorCS2 122 kDa chain; SorCS2 104 kDa chain; SorCS2 18 kDa chain]

1

8

Small-scale

0.501

High

389782

TTHY
Transthyretin

1

0

High-throughput

0.486

High

417897

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.486

High

466559

RCC1
Regulator of chromosome condensation

1

0

High-throughput

0.486

High

466565

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.486

High

466585

UFD1
Ubiquitin recognition factor in ER-associated degradation protein 1

1

0

High-throughput

0.486

High

136656

TRAF5
TNF receptor-associated factor 5

1

20

Small-scale

0.479

High

177769

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

18

Small-scale

0.479

High

466563

SHC1
SHC-transforming protein 1

1

10

Small-scale

0.479

High

466572

TRAF1
TNF receptor-associated factor 1

1

20

Small-scale

0.479

High

466573

TRAF3
TNF receptor-associated factor 3

1

20

Small-scale

0.479

High

466576

ITA9
Integrin alpha-9

1

3

Small-scale

0.479

High

466579

NTRK2
BDNF/NT-3 growth factors receptor

1

14

Small-scale

0.479

High

466583

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

20

Small-scale

0.479

High

466601

SORC3
VPS10 domain-containing receptor SorCS3

1

8

Small-scale

0.479

High

466567

BACE1
Beta-secretase 1

1

0

Small-scale

0.458

High

466569

BEX3
Protein BEX3

1

3

Small-scale

0.445

High

466577

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

2

High-throughput

0.445

High

466584

TSC1
Hamartin

1

6

Small-scale

0.445

High

466597

BEX1
Protein BEX1

1

3

Small-scale

0.437

High

254749

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

466602

TCF19
Transcription factor 19

1

0

Small-scale

0.288

High


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Last updated: 11Aug2025