Protein: VTNC
Vitronectin (VN) (S-protein) (Serum-spreading factor) (V75) [Cleaved into: Vitronectin V65 subunit; Vitronectin V10 subunit; Somatomedin-B]

Gene: VTNC, VTN
Organism: Homo sapiens
Interactions: 144
UniProt ID: P04004

Gene Ontology (top 5):
GO:0005044 - scavenger receptor activity
GO:0005178 - integrin binding
GO:0005201 - extracellular matrix structural constituent
GO:0005518 - collagen binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

372974

PAI1
Plasminogen activator inhibitor 1

2

2

Small-scale

0.778

High

373016

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

3

2

Small-scale

0.675

High

372992

ITB5
Integrin beta-5

3

4

Small-scale

0.667

High

372969

VTNC
Vitronectin

1

3

Small-scale

0.647

High

215513

CF410
Cilia- and flagella-associated protein 410

3

0

High-throughput

0.646

High

226219

PRKN
E3 ubiquitin-protein ligase parkin

3

5

High-throughput

0.640

High

373074

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

4

4

High-throughput

0.637

High

258891

RTN2
Reticulon-2

2

1

High-throughput

0.628

High

373035

KTN1
Kinectin

2

2

High-throughput

0.628

High

373063

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

2

1

High-throughput

0.628

High

373021

CUL7
Cullin-7

3

1

High-throughput

0.609

High

373048

DLG3
Disks large homolog 3

2

1

High-throughput

0.606

High

372972

A4
Amyloid-beta precursor protein

2

3

Small-scale

0.602

High

372976

ITAV
Integrin alpha-V

2

5

Small-scale

0.595

High

372997

1433T
14-3-3 protein theta

2

0

High-throughput

0.576

High

373056

NEK1
Serine/threonine-protein kinase Nek1

2

3

High-throughput

0.574

High

373064

WDR33
pre-mRNA 3' end processing protein WDR33

2

3

High-throughput

0.574

High

373068

TARA
TRIO and F-actin-binding protein

2

1

High-throughput

0.574

High

373078

RAI14
Ankycorbin

2

1

High-throughput

0.574

High

373081

RNF14
E3 ubiquitin-protein ligase RNF14

2

5

High-throughput

0.574

High

373086

ZN777
Zinc finger protein 777

2

1

High-throughput

0.574

High

373025

DLG2
Disks large homolog 2

2

1

High-throughput

0.553

High

373077

SNTG1
Gamma-1-syntrophin

2

3

High-throughput

0.553

High

372985

CFTR
Cystic fibrosis transmembrane conductance regulator

2

1

High-throughput

0.549

High

126341

MATN2
Matrilin-2

1

10

High-throughput

0.536

High

198363

KLK10
Kallikrein-10

1

7

High-throughput

0.536

High

372999

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

373042

RHBL4
Rhomboid-related protein 4

1

3

High-throughput

0.536

High

373060

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

1

High-throughput

0.536

High

372983

ADHX
Alcohol dehydrogenase class-3

1

0

High-throughput

0.518

High

373010

CBX1
Chromobox protein homolog 1

1

0

High-throughput

0.518

High

373055

ADTRP
Androgen-dependent TFPI-regulating protein

1

0

High-throughput

0.518

High

215794

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

0

High-throughput

0.513

High

373031

HACD2
Very-long-chain

1

0

High-throughput

0.513

High

373058

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.513

High

373005

GEM
GTP-binding protein GEM

1

1

High-throughput

0.508

High

351126

EGF
Pro-epidermal growth factor

1

2

Small-scale

0.501

High

351209

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

6

Small-scale

0.501

High

372978

ITA2B
Integrin alpha-IIb

1

5

Small-scale

0.501

High

372979

ITA5
Integrin alpha-5

1

5

Small-scale

0.501

High

372981

SPRC
SPARC

1

3

Small-scale

0.501

High

372996

IBP5
Insulin-like growth factor-binding protein 5

1

2

Small-scale

0.501

High

373008

TGFB2
Transforming growth factor beta-2 proprotein

1

6

Small-scale

0.501

High

373041

RHXF1
Rhox homeobox family member 1

1

3

High-throughput

0.494

High

373090

ETV7
Transcription factor ETV7

1

1

High-throughput

0.494

High

373012

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

1

High-throughput

0.489

High

373027

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

1

High-throughput

0.489

High

373030

MPRIP
Myosin phosphatase Rho-interacting protein

1

3

High-throughput

0.489

High

373051

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

2

High-throughput

0.489

High

373070

SIA7D
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase

1

2

High-throughput

0.489

High

373076

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.489

High

373084

PHF11
PHD finger protein 11

1

1

High-throughput

0.489

High

373085

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

3

High-throughput

0.489

High

335020

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.481

High

345164

KNG1
Kininogen-1

1

0

Small-scale

0.480

High

351588

COLI
Pro-opiomelanocortin

1

0

Small-scale

0.480

High

352339

IGF2
Insulin-like growth factor II

1

0

Small-scale

0.480

High

372980

FGF2
Fibroblast growth factor 2

1

0

Small-scale

0.480

High

372986

HGF
Hepatocyte growth factor

1

0

Small-scale

0.480

High

372987

PVR
Poliovirus receptor

1

0

Small-scale

0.480

High

372988

VEGFA
Vascular endothelial growth factor A, long form

1

0

Small-scale

0.480

High

372989

KPCA
Protein kinase C alpha type

1

0

Small-scale

0.480

High

372991

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

Small-scale

0.480

High

373036

C163A
Scavenger receptor cysteine-rich type 1 protein M130

1

0

Small-scale

0.480

High

373038

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

Small-scale

0.480

High

373065

LACRT
Extracellular glycoprotein lacritin

1

0

Small-scale

0.480

High

181029

INSI1
Insulin-induced gene 1 protein

1

1

High-throughput

0.479

High

372973

ITB3
Integrin beta-3

1

4

Small-scale

0.479

High

372977

CATB
Cathepsin B

1

1

Small-scale

0.479

High

373011

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.479

High

373047

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

373069

CHM4B
Charged multivesicular body protein 4b

1

1

High-throughput

0.479

High

373089

INSI2
Insulin-induced gene 2 protein

1

1

High-throughput

0.479

High

373039

LNX2
Ligand of Numb protein X 2

1

2

High-throughput

0.464

High

373017

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.460

High

298036

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

373004

ACLY
ATP-citrate synthase

1

0

High-throughput

0.458

High

373023

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

373054

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

373072

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

0

High-throughput

0.458

High

373079

ATX10
Ataxin-10

1

0

High-throughput

0.458

High

373002

AMPH
Amphiphysin

1

1

Small-scale

0.457

High

372993

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

3

High-throughput

0.445

High

373066

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

1

High-throughput

0.445

High

148265

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.437

High

243776

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.437

High

308303

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

372970

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.437

High

372971

GCR
Glucocorticoid receptor

1

3

High-throughput

0.437

High

373015

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.437

High

373037

CUL9
Cullin-9

1

2

High-throughput

0.437

High

373052

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.437

High

373075

ANLN
Anillin

1

1

High-throughput

0.437

High

373018

MTA1
Metastasis-associated protein MTA1

1

0

Small-scale

0.426

High

372975

JUN
Transcription factor Jun

1

6

High-throughput

0.407

High

373088

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

1

High-throughput

0.407

High

158722

HAT1
Histone acetyltransferase type B catalytic subunit

2

0

High-throughput

0.328

High

275675

RPP40
Ribonuclease P protein subunit p40

2

0

High-throughput

0.328

High

319427

RPP29
Ribonuclease P protein subunit p29

2

0

High-throughput

0.328

High

372982

GLI4
Zinc finger protein GLI4

2

0

High-throughput

0.328

High

372990

HXB9
Homeobox protein Hox-B9

2

0

High-throughput

0.328

High

373006

NP1L1
Nucleosome assembly protein 1-like 1

2

0

High-throughput

0.328

High

373007

RRP1
Ribosomal RNA processing protein 1 homolog A

2

0

High-throughput

0.328

High

373014

OTUD4
OTU domain-containing protein 4

2

0

High-throughput

0.328

High

373022

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

2

0

High-throughput

0.328

High

373028

MBOA5
Lysophospholipid acyltransferase 5

2

0

High-throughput

0.328

High

373032

GRIN1
G protein-regulated inducer of neurite outgrowth 1

2

0

High-throughput

0.328

High

373034

FBX33
F-box only protein 33

2

0

High-throughput

0.328

High

373043

ZN483
Zinc finger protein 483

2

0

High-throughput

0.328

High

373045

PTCD2
Pentatricopeptide repeat-containing protein 2, mitochondrial

2

0

High-throughput

0.328

High

373053

ISOC1
Isochorismatase domain-containing protein 1

2

0

High-throughput

0.328

High

373071

ZN696
Zinc finger protein 696

2

0

High-throughput

0.328

High

373073

MRS2
Magnesium transporter MRS2 homolog, mitochondrial

2

0

High-throughput

0.328

High

373082

ARMX3
Armadillo repeat-containing X-linked protein 3

2

0

High-throughput

0.328

High

373087

DCAF1
DDB1- and CUL4-associated factor 1

2

0

High-throughput

0.328

High

373083

UBQL2
Ubiquilin-2

2

0

High-throughput

0.316

High

372994

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

0

High-throughput

0.282

High

373000

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

0

High-throughput

0.282

High

373009

CRADD
Death domain-containing protein CRADD

1

0

High-throughput

0.282

High

372984

CDK4
Cyclin-dependent kinase 4

1

0

High-throughput

0.279

Low

372998

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

0

High-throughput

0.279

Low

373003

RBM5
RNA-binding protein 5

1

0

High-throughput

0.279

Low

373020

TTLL4
Tubulin monoglutamylase TTLL4

1

0

High-throughput

0.279

Low

373029

RHGBA
Rho GTPase-activating protein 11A

1

0

High-throughput

0.279

Low

373033

TRM11
tRNA

1

0

High-throughput

0.279

Low

373040

LEMD2
LEM domain-containing protein 2

1

0

High-throughput

0.279

Low

373044

HASP
Serine/threonine-protein kinase haspin

1

0

High-throughput

0.279

Low

373050

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.279

Low

373062

TR61B
tRNA

1

0

High-throughput

0.279

Low

373067

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.279

Low

373049

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.265

Low

373057

PASK
PAS domain-containing serine/threonine-protein kinase

1

0

Small-scale

0.261

Low

373001

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.251

Low

373024

SIX1
Homeobox protein SIX1

1

0

High-throughput

0.251

Low

267837

EED
Polycomb protein EED

1

0

High-throughput

0.249

Low

373013

VIGLN
Vigilin

1

0

High-throughput

0.249

Low

373019

TFDP2
Transcription factor Dp-2

1

0

High-throughput

0.249

Low

373026

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

373046

NUDC2
NudC domain-containing protein 2

1

0

High-throughput

0.249

Low

373061

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

373080

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.249

Low

373059

THIOM
Thioredoxin, mitochondrial

1

0

High-throughput

0.238

Low

372995

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024