HitPredict

Interactor 1: PLXB2 (O15031)
Plexin-B2 (MM1)
Gene: PLXNB2

Interactor 2: ARHGB (O15085)
Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF)
Gene: ARHGEF11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	12123608, 12183458
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1838 Hs			1 1522
+	Mm
		71306 PLXB2_MOUSE (1-1838): 0: 2370: 87.35		Q68FM7_MOUSE (1-1522): 0: 879: 81.95
+	Hs
		165264 PLXB2_HUMAN (1-1838): 0: 2441: 100.00		ARHGC_HUMAN (6-1457): 0: 596: 29.71
+	Hs
		167118 PLXB3_HUMAN (26-1838): 0: 2045: 39.61		ARHGB_HUMAN (1-1522): 0: 936: 100.00
+	Mm
		1148467 PLXB3_MOUSE (26-1838): 0: 2057: 39.41		Q68FM7_MOUSE (1-1522): 0: 879: 81.95
+	Dm
		1001987 Q0KIF1_DROME (389-1834): 0: 1751: 33.12		Q9U7D8_DROME (741-930): 2.82e-14: 80.5: 25.64
+	Hs
		167053 PLXB1_HUMAN (618-818): 1.28e-12: 75.5: 20.64		ARHGB_HUMAN (1-1522): 0: 936: 100.00
+	Mm
		1148466 PLXB1_MOUSE (493-811): 3.67e-13: 77.4: 14.95		Q68FM7_MOUSE (1-1522): 0: 879: 81.95
+	Hs
		1329264 SEM6A_HUMAN (5-518): 7.22e-131: 438: 18.80		ITSN2_HUMAN (713-1100): 1.19e-86: 315: 23.56
+	Mm
		101476 MET_MOUSE (687-1228): 1.58e-89: 324: 19.96		FARP1_MOUSE (205-1177): 5.14e-119: 402: 15.19
+	Mm
		110600 MET_MOUSE (687-1228): 1.58e-89: 324: 19.96		H3BJU7_MOUSE (526-1485): 3.01e-115: 389: 17.16
+	Hs
		441580 MET_HUMAN (746-1153): 4.48e-87: 316: 21.38		VAV3_HUMAN (553-1281): 6.21e-116: 388: 15.46
+	Hs
		441472 MET_HUMAN (746-1153): 4.48e-87: 316: 21.38		VAV2_HUMAN (553-1306): 2.19e-109: 370: 14.78
+	Mm
		1208656 PLXB1_MOUSE (493-811): 3.67e-13: 77.4: 14.95		ARHGC_MOUSE (6-1457): 0: 606: 31.01
+	Hs
		195990 PLXB1_HUMAN (618-818): 1.28e-12: 75.5: 20.64		ARHGC_HUMAN (6-1457): 0: 596: 29.71
+	Mm
		554983 MET_MOUSE (687-1228): 1.58e-89: 324: 19.96		TRIO_MOUSE (348-1351): 3.57e-79: 292: 12.46
+	Mm
		57826 MET_MOUSE (687-1228): 1.58e-89: 324: 19.96		KALRN_MOUSE (337-1518): 9.23e-70: 262: 11.92
+	Dm
		55338 Q0E8S4_DROME (25-511): 4.63e-69: 254: 20.07		A1ZAN6_DROME (48-249): 2.14e-46: 186: 30.73
+	Dm
		55339 SEM1A_DROME (25-511): 4.26e-69: 254: 20.07		A1ZAN6_DROME (48-249): 2.14e-46: 186: 30.73
+	Mm
		100126 MET_MOUSE (687-1228): 1.58e-89: 324: 19.96		F6U8U1_MOUSE (735-891): 4.24e-13: 74.3: 30.00
+	Dm
		1097383 SEM1A_DROME (25-511): 4.26e-69: 254: 20.07		Q9U7D8_DROME (741-930): 2.82e-14: 80.5: 25.64