HitPredict

Interactor 1: SET1A (O15047)
Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)
Gene: SETD1A

Interactor 2: NUP50 (Q9UKX7)
Nuclear pore complex protein Nup50 (50 kDa nucleoporin) (Nuclear pore-associated protein 60 kDa-like) (Nucleoporin Nup50)
Gene: NUP50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1707 Hs			1 468
+	Hs
		1080468 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Hs
		975341 KMT2A_HUMAN (1094-1707): 3.48e-69: 261: 21.28		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Hs
		1317725 NSD3_HUMAN (1561-1706): 5.1e-55: 213: 30.20		NUP50_HUMAN (1-468): 1.01e-131: 390: 100.00
+	Hs
		796752 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		RANG_HUMAN (316-466): 8.74e-42: 149: 19.38
+	Hs
		834755 EZH2_HUMAN (1161-1690): 6.02e-75: 268: 14.71		RBP2_HUMAN (212-468): 1.6e-36: 146: 17.60