HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: SMN (Q16637)
Survival motor neuron protein (Component of gems 1) (Gemin-1)
Gene: SMN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030424 - axon
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 294
+	Hs
		1084933 LSM7_HUMAN (8-89): 4.34e-27: 98.5: 29.89		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Hs
		927964 RSMN_HUMAN (6-86): 1.43e-24: 95.8: 23.86		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Hs
		912053 RUXG_HUMAN (4-79): 1.75e-25: 93.5: 30.26		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Hs
		538980 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Hs
		68426 RUXGL_HUMAN (4-79): 1.11e-22: 86.2: 28.95		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Mm
		646098 RSMB_MOUSE (6-86): 1.3e-23: 93.1: 23.86		SMN_MOUSE (1-292): 6.42e-139: 395: 81.85
+	Dm
		984948 RSMB_DROME (6-74): 5.11e-24: 93.1: 26.32		SMN_DROME (27-179): 9.4e-54: 176: 24.68
+	Hs
		278909 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		SPF30_HUMAN (44-158): 1.19e-31: 119: 32.17