Protein: EYA3
Eyes absent homolog 3 (EC 3.1.3.48)

Gene: EYA3
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q99504

Gene Ontology (top 5):
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1304309

SIX2
Homeobox protein SIX2

2

20

High-throughput

0.811

High

1230645

SIX5
Homeobox protein SIX5

2

20

Small-scale

0.789

High

1050758

FHL2
Four and a half LIM domains protein 2

3

1

High-throughput

0.656

High

1069220

TCAL1
Transcription elongation factor A protein-like 1

3

0

High-throughput

0.638

High

530955

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.630

High

1304300

EYA3
Eyes absent homolog 3

1

5

High-throughput

0.618

High

802711

CRK
Adapter molecule crk

2

2

High-throughput

0.594

High

1284776

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

555613

H2AX
Histone H2AX

1

1

Small-scale

0.515

High

422270

NFL
Neurofilament light polypeptide

1

1

High-throughput

0.515

High

500042

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.515

High

642790

ELAV4
ELAV-like protein 4

1

0

High-throughput

0.511

High

305192

UBE4B
Ubiquitin conjugation factor E4 B

1

0

High-throughput

0.493

High

281843

WFS1
Wolframin

1

0

High-throughput

0.493

High

791900

HD
Huntingtin

1

0

High-throughput

0.493

High

840802

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

848111

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.493

High

1271884

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

1304312

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

228459

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

304305

UBR5
E3 ubiquitin-protein ligase UBR5

1

1

High-throughput

0.479

High

437454

4F2
Amino acid transporter heavy chain SLC3A2

1

1

High-throughput

0.479

High

548945

NDKA
Nucleoside diphosphate kinase A

1

1

High-throughput

0.479

High

573056

PRS6A
26S proteasome regulatory subunit 6A

1

1

High-throughput

0.479

High

668931

PML
Protein PML

1

1

High-throughput

0.479

High

679161

TLX1
T-cell leukemia homeobox protein 1

1

4

High-throughput

0.479

High

684972

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

831623

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.479

High

935155

H31
Histone H3.1

1

1

High-throughput

0.479

High

952577

H33
Histone H3.3

1

1

High-throughput

0.479

High

967381

EWS
RNA-binding protein EWS

1

5

High-throughput

0.479

High

980852

TLE3
Transducin-like enhancer protein 3

1

6

High-throughput

0.479

High

1024744

TRAF3
TNF receptor-associated factor 3

1

1

High-throughput

0.479

High

1040917

MTMR2
Myotubularin-related protein 2

1

1

High-throughput

0.479

High

1040947

MTMR3
Myotubularin-related protein 3

1

1

High-throughput

0.479

High

1254899

SP7
Transcription factor Sp7

1

1

High-throughput

0.479

High

1269437

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1288262

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

1

High-throughput

0.479

High

1304306

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

1304307

GRPE1
GrpE protein homolog 1, mitochondrial

1

1

High-throughput

0.479

High

1304311

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

231691

KIF1B
Kinesin-like protein KIF1B

1

1

High-throughput

0.470

High

131054

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

381025

SEMG1
Semenogelin-1

1

0

High-throughput

0.458

High

387364

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

521295

SKI
Ski oncogene

1

0

Small-scale

0.458

High

589914

TBP
TATA-box-binding protein

1

0

High-throughput

0.458

High

594616

PSB1
Proteasome subunit beta type-1

1

0

High-throughput

0.458

High

850162

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.458

High

875250

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

913341

PRS10
26S proteasome regulatory subunit 10B

1

0

High-throughput

0.458

High

1139428

ECM29
Proteasome adapter and scaffold protein ECM29

1

0

High-throughput

0.458

High

1188766

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1192181

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1257150

DI3L1
DIS3-like exonuclease 1

1

0

High-throughput

0.458

High

1301736

WRIP1
ATPase WRNIP1

1

0

High-throughput

0.458

High

1303909

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.458

High

1304301

SEN34
tRNA-splicing endonuclease subunit Sen34

1

0

High-throughput

0.458

High

1304304

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

1304308

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1304310

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

297091

TOM70
Mitochondrial import receptor subunit TOM70

1

2

High-throughput

0.437

High

618498

ANFC
C-type natriuretic peptide [Cleaved into: CNP-22; CNP-29; CNP-53]

1

1

High-throughput

0.437

High

725861

SOAT1
Sterol O-acyltransferase 1

1

1

High-throughput

0.437

High

1219173

CC28A
Coiled-coil domain-containing protein 28A

1

1

High-throughput

0.437

High

1304303

TIM21
Mitochondrial import inner membrane translocase subunit Tim21

1

1

High-throughput

0.437

High

1130481

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1304313

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

2

0

High-throughput

0.305

High

234571

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.282

High

1216541

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

323984

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

47298

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

557492

PECA1
Platelet endothelial cell adhesion molecule

1

0

High-throughput

0.268

Low

882794

STX17
Syntaxin-17

1

0

High-throughput

0.249

Low

1304302

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.249

Low

1304305

T126A
Transmembrane protein 126A

1

0

High-throughput

0.249

Low

886324

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024