Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB
Interactor 2: M3K11 (Q16584)
Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25) (Mixed lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase)
Gene: MAP3K11
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.57 | 1.00 | 0.757 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10713178 |
| Identification Methods | enzymatic study, anti tag coimmunoprecipitation, in-gel kinase assay |
| Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~Pkinase |
| Common GO terms | GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | At | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 11Aug2025
