Interactor 1: NPC1 (O15118)
NPC intracellular cholesterol transporter 1 (Niemann-Pick C1 protein)
Gene: NPC1

Interactor 2: TLR3 (O15455)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 33144569
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004888 - transmembrane signaling receptor activity
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0038023 - signaling receptor activity
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 904
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024