HitPredict

Interactor 1: SCAM2 (O15127)
Secretory carrier-associated membrane protein 2 (Secretory carrier membrane protein 2)
Gene: SCAMP2

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane GO:0032588 - trans-Golgi network membrane GO:0043231 - intracellular membrane-bounded organelle GO:0055038 - recycling endosome membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 329 Hs			1 100
+	Hs
		168400 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		168363 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51
+	Hs
		168444 SCAM1_HUMAN (1-314): 2.05e-138: 397: 53.80		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		727 A0A087WXB0_HUMAN (1-314): 2.34e-125: 363: 50.48		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		731 A0A087WXB0_HUMAN (1-314): 2.34e-125: 363: 50.48		VAMP8_HUMAN (6-82): 1.84e-22: 85: 35.07
+	Hs
		156429 SCAM3_HUMAN (6-316): 1.55e-121: 354: 49.69		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57
+	Hs
		1079381 SCAM5_HUMAN (116-314): 3.93e-80: 245: 49.75		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		261694 SCAM5_HUMAN (116-314): 3.93e-80: 245: 49.75		VAMP4_HUMAN (3-82): 3.5e-25: 93.5: 40.00