HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: TRI74 (Q86UV6)
Tripartite motif-containing protein 74 (Tripartite motif-containing protein 50C)
Gene: TRIM74

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 250
+	Hs
		169419 HGS_HUMAN (1-777): 1.57e-105: 343: 100.00		TRI27_HUMAN (1-250): 6.65e-58: 193: 26.46
+	Hs
		169632 HGS_HUMAN (1-777): 1.57e-105: 343: 100.00		TRI69_HUMAN (1-249): 4.35e-55: 185: 19.37
+	Hs
		169805 HGS_HUMAN (1-777): 1.57e-105: 343: 100.00		TRI17_HUMAN (1-250): 1.91e-54: 183: 21.92
+	Hs
		169780 HGS_HUMAN (1-777): 1.57e-105: 343: 100.00		TRI10_HUMAN (1-250): 2.07e-53: 181: 22.69
+	Hs
		169626 HGS_HUMAN (1-777): 1.57e-105: 343: 100.00		TRI73_HUMAN (1-250): 1.77e-50: 167: 99.60
+	Hs
		3374 A0A0S2Z4Q4_HUMAN (1-688): 1.44e-48: 185: 41.85		TRI27_HUMAN (1-250): 6.65e-58: 193: 26.46
+	Hs
		3385 A0A0S2Z4Q4_HUMAN (1-688): 1.44e-48: 185: 41.85		TRI69_HUMAN (1-249): 4.35e-55: 185: 19.37
+	Hs
		1256909 TM1L2_HUMAN (5-448): 7.23e-50: 185: 17.17		TRI10_HUMAN (1-250): 2.07e-53: 181: 22.69
+	Hs
		1315294 PKHF2_HUMAN (52-243): 9.18e-36: 137: 21.32		TRI22_HUMAN (1-250): 4.23e-61: 201: 24.71