HitPredict

Interactor 1: WDR46 (O15213)
WD repeat-containing protein 46 (WD repeat-containing protein BING4)
Gene: WDR46

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35509820
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 610 Hs			1 465
+	Hs
		229055 PRP19_HUMAN (10-474): 4.42e-82: 268: 14.70		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226765 LIS1_HUMAN (233-528): 1.17e-68: 230: 10.56		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227054 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228276 FBXW7_HUMAN (303-522): 5.74e-37: 148: 12.00		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227540 TAF5_HUMAN (201-466): 5.07e-33: 137: 16.73		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		227099 GBB2_HUMAN (291-489): 3.52e-28: 117: 8.50		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228555 KTNB1_HUMAN (148-287): 1.02e-19: 95.2: 12.59		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Sc
		477301 UTP7_YEAST (91-608): 2.22e-88: 286: 36.98		UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72
+	Hs
		228623 WDR33_HUMAN (161-302): 7.8e-17: 86.8: 8.05		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228868 NLE1_HUMAN (43-222): 1.83e-14: 78.2: 12.78		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		1281514 FBXW7_HUMAN (303-522): 5.74e-37: 148: 12.00		ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67
+	Hs
		476564 PRP19_HUMAN (10-474): 4.42e-82: 268: 14.70		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Sc
		477239 TAF5_YEAST (199-390): 1.27e-33: 138: 17.77		UBI4P_YEAST (1-229): 3.48e-61: 205: 18.72
+	Hs
		475563 WDR5_HUMAN (309-535): 1.07e-51: 183: 14.35		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		476151 FBXW7_HUMAN (303-522): 5.74e-37: 148: 12.00		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475589 GBB2_HUMAN (291-489): 3.52e-28: 117: 8.50		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		476334 WDR33_HUMAN (161-302): 7.8e-17: 86.8: 8.05		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47