HitPredict

Interactor 1: LAMA5 (O15230)
Laminin subunit alpha-5 (Laminin-10 subunit alpha) (Laminin-11 subunit alpha) (Laminin-15 subunit alpha)
Gene: LAMA5

Interactor 2: OIT3 (Q8WWZ8)
Oncoprotein-induced transcript 3 protein (Liver-specific zona pellucida domain-containing protein)
Gene: OIT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3695 Hs			1 545
+	Hs
		172715 LAMA5_HUMAN (1-3695): 0: 2212: 100.00		FBLN5_HUMAN (86-393): 2.73e-43: 161: 20.25
+	Hs
		172655 LAMA5_HUMAN (1-3695): 0: 2212: 100.00		FBLN2_HUMAN (11-195): 7.64e-10: 63.7: 14.49
+	Dm
		90684 NOTCH_DROME (1323-2246): 9.26e-77: 288: 13.66		E1JHA6_DROME (22-382): 8.15e-20: 96.1: 13.47
+	Hs
		980375 NOTC2_HUMAN (1360-2243): 4.79e-72: 273: 12.64		LTBP1_HUMAN (135-365): 2.94e-22: 103: 15.92
+	Hs
		877434 LAMB2_HUMAN (756-892): 9.92e-17: 90.4: 31.43		OIT3_HUMAN (1-545): 2.33e-87: 281: 100.00
+	Dm
		422709 NOTCH_DROME (1323-2246): 9.26e-77: 288: 13.66		NOTCH_DROME (2-360): 1.23e-09: 63.4: 11.11
+	Hs
		724367 NOTC2_HUMAN (1360-2243): 4.79e-72: 273: 12.64		FBN2_HUMAN (18-252): 8.87e-13: 73.8: 19.09
+	Hs
		612843 NOTC2_HUMAN (1360-2243): 4.79e-72: 273: 12.64		FBLN1_HUMAN (63-216): 1.31e-11: 69.4: 21.11
+	Hs
		804213 NOTC2_HUMAN (1360-2243): 4.79e-72: 273: 12.64		NOTC1_HUMAN (5-356): 8.24e-10: 64.2: 9.55
+	Dr
		804161 NOTC1_DANRE (1347-2236): 3.88e-68: 259: 13.28		Q1A5L2_DANRE (216-383): 2.53e-11: 68.8: 9.61
+	Mm
		82715 CNTP2_MOUSE (3346-3687): 3.02e-31: 137: 13.25		B9EJ72_MOUSE (7-318): 1.51e-29: 126: 10.64
+	Hs
		804163 NOTC1_HUMAN (1638-2252): 1.9e-36: 155: 11.76		NOTC1_HUMAN (5-356): 8.24e-10: 64.2: 9.55
+	Hs
		877405 LAMB2_HUMAN (756-892): 9.92e-17: 90.4: 31.43		FBLN3_HUMAN (56-283): 9.81e-31: 127: 17.55
+	Mm
		1112697 CNTP2_MOUSE (3346-3687): 3.02e-31: 137: 13.25		TEN4_MOUSE (4-160): 1.37e-12: 73: 10.93
+	Mm
		1321670 CNTP2_MOUSE (3346-3687): 3.02e-31: 137: 13.25		TEN1_MOUSE (9-160): 2.38e-09: 62.6: 10.18
+	Dm
		246764 LAMA_DROME (2961-3294): 9e-21: 103: 15.88		TENM_DROME (212-386): 2.83e-14: 78.4: 8.89
+	Dm
		422742 LAMA_DROME (2961-3294): 9e-21: 103: 15.88		NOTCH_DROME (2-360): 1.23e-09: 63.4: 11.11
+	Mm
		1112699 NRX1A_MOUSE (2963-3117): 1.9e-12: 76.2: 13.42		TEN4_MOUSE (4-160): 1.37e-12: 73: 10.93
+	Mm
		103557 G5E874_MOUSE (299-434): 1.36e-12: 76.5: 24.82		FBLN2_MOUSE (11-195): 3.74e-11: 68: 13.53
+	Mm
		103558 G5E874_MOUSE (299-434): 1.36e-12: 76.5: 24.82		FBLN1_MOUSE (165-263): 2.58e-10: 65.1: 39.60