HitPredict

Interactor 1: CASC3 (O15234)
Protein CASC3 (Cancer susceptibility candidate gene 3 protein) (Metastatic lymph node gene 51 protein) (MLN 51) (Protein barentsz) (Btz)
Gene: CASC3

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 703 Hs			1 559
+	Hs
		172859 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		172855 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		ELAV2_HUMAN (223-553): 1.56e-45: 165: 14.80
+	Hs
		172895 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		PABP5_HUMAN (133-308): 3.43e-45: 165: 23.86
+	Hs
		1054314 MDC1_HUMAN (26-703): 5.64e-39: 157: 9.51		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		172881 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		CELF5_HUMAN (226-307): 1.82e-18: 90.2: 25.61
+	Hs
		172817 CASC3_HUMAN (1-703): 3.04e-79: 269: 100.00		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1054463 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		RBM39_HUMAN (113-555): 5.61e-70: 235: 19.78
+	Hs
		516595 KMT2C_HUMAN (265-696): 9.73e-14: 77.5: 13.27		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64
+	Hs
		1031402 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		PABP4_HUMAN (457-550): 1.89e-10: 65.7: 10.64
+	Hs
		516606 ATX2L_HUMAN (106-703): 3.11e-11: 69.1: 10.52		PABP1_HUMAN (457-550): 3.84e-10: 64.5: 10.64