Protein: ARHGA
Rho guanine nucleotide exchange factor 10

Gene: ARHGA, ARHGEF10
Organism: Homo sapiens
Interactions: 84
UniProt ID: O15013

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0019894 - kinesin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

174272

ARGAL
Rho guanine nucleotide exchange factor 10-like protein

3

16

High-throughput

0.839

High

174232

RB11A
Ras-related protein Rab-11A

2

3

High-throughput

0.754

High

174259

ARG39
Rho guanine nucleotide exchange factor 39

2

19

High-throughput

0.737

High

174278

HECD1
E3 ubiquitin-protein ligase HECTD1

2

7

Small-scale

0.705

High

174238

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

17

High-throughput

0.698

High

158379

RFXK
DNA-binding protein RFXANK

1

13

High-throughput

0.691

High

174226

CRK
Adapter molecule crk

1

20

High-throughput

0.691

High

174268

SPSB2
SPRY domain-containing SOCS box protein 2

4

17

High-throughput

0.683

High

174221

EPHA2
Ephrin type-A receptor 2

2

20

High-throughput

0.675

High

174205

DNJB5
DnaJ homolog subfamily B member 5

3

8

High-throughput

0.656

High

174251

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

3

1

High-throughput

0.656

High

174265

RSPRY
RING finger and SPRY domain-containing protein 1

3

7

High-throughput

0.656

High

174269

SETD2
Histone-lysine N-methyltransferase SETD2

3

2

High-throughput

0.656

High

174281

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

3

1

High-throughput

0.656

High

174229

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.647

High

174230

RHOA
Transforming protein RhoA

1

20

High-throughput

0.647

High

174233

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.647

High

174216

RAB3B
Ras-related protein Rab-3B

1

8

High-throughput

0.618

High

174241

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.618

High

174255

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

174211

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.611

High

174235

SSBP2
Single-stranded DNA-binding protein 2

2

3

High-throughput

0.611

High

174263

SPSB4
SPRY domain-containing SOCS box protein 4

2

20

High-throughput

0.601

High

174266

RNF31
E3 ubiquitin-protein ligase RNF31

2

12

High-throughput

0.584

High

174254

PKHG7
Pleckstrin homology domain-containing family G member 7

1

15

High-throughput

0.575

High

174208

S10A8
Protein S100-A8

2

3

High-throughput

0.571

High

174219

DNJB1
DnaJ homolog subfamily B member 1

2

8

High-throughput

0.571

High

174220

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

14

High-throughput

0.571

High

174280

SGT1
Protein SGT1 homolog

2

2

High-throughput

0.571

High

174202

HS12A
Heat shock 70 kDa protein 12A

1

1

High-throughput

0.536

High

174206

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

174217

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

High-throughput

0.536

High

174257

HOOK3
Protein Hook homolog 3

1

20

High-throughput

0.536

High

174260

WDR48
WD repeat-containing protein 48

1

14

High-throughput

0.536

High

174264

EFMT3
EEF1A lysine methyltransferase 3

1

2

High-throughput

0.536

High

174270

UBXN6
UBX domain-containing protein 6

1

2

High-throughput

0.536

High

174273

KLH14
Kelch-like protein 14

1

3

High-throughput

0.536

High

174276

HSPB8
Heat shock protein beta-8

1

3

High-throughput

0.536

High

174277

BAG5
BAG family molecular chaperone regulator 5

1

2

High-throughput

0.536

High

174199

KIF3B
Kinesin-like protein KIF3B

1

10

Small-scale

0.535

High

174279

ALK
ALK tyrosine kinase receptor

2

20

High-throughput

0.533

High

174214

HMGA1
High mobility group protein HMG-I/HMG-Y

1

2

High-throughput

0.515

High

174209

ICAM1
Intercellular adhesion molecule 1

1

4

High-throughput

0.489

High

174243

SF3B3
Splicing factor 3B subunit 3

1

3

High-throughput

0.489

High

174247

INF2
Inverted formin-2

1

3

High-throughput

0.489

High

174248

MICB
MHC class I polypeptide-related sequence B

1

3

High-throughput

0.489

High

174240

FHL3
Four and a half LIM domains protein 3

1

8

High-throughput

0.481

High

174204

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

174210

PGFRB
Platelet-derived growth factor receptor beta

1

20

High-throughput

0.479

High

174212

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

174215

CXA1
Gap junction alpha-1 protein

1

4

High-throughput

0.479

High

174222

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

7

High-throughput

0.479

High

174223

CASPE
Caspase-14

1

1

High-throughput

0.479

High

174224

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

174225

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.479

High

174227

VASP
Vasodilator-stimulated phosphoprotein

1

7

High-throughput

0.479

High

174228

NP1L1
Nucleosome assembly protein 1-like 1

1

1

High-throughput

0.479

High

174231

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

174234

CXAR
Coxsackievirus and adenovirus receptor

1

5

High-throughput

0.479

High

174237

TF65
Transcription factor p65

1

6

High-throughput

0.479

High

174239

DCTN2
Dynactin subunit 2

1

2

High-throughput

0.479

High

174244

ZYX
Zyxin

1

9

High-throughput

0.479

High

174245

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.479

High

174246

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.479

High

174249

RHG31
Rho GTPase-activating protein 31

1

12

High-throughput

0.479

High

174250

GRDN
Girdin

1

20

High-throughput

0.479

High

174258

DYR2
Dihydrofolate reductase 2, mitochondrial

1

1

High-throughput

0.479

High

174262

FBXW7
F-box/WD repeat-containing protein 7

1

6

High-throughput

0.479

High

174275

XPO7
Exportin-7

1

9

High-throughput

0.479

High

174242

RNPS1
RNA-binding protein with serine-rich domain 1

1

11

High-throughput

0.445

High

174271

ELL3
RNA polymerase II elongation factor ELL3

1

2

High-throughput

0.445

High

174200

BET1
BET1 homolog

1

2

High-throughput

0.437

High

174201

STX7
Syntaxin-7

1

5

High-throughput

0.437

High

174203

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.437

High

174207

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.437

High

174213

LYL1
Protein lyl-1

1

2

High-throughput

0.437

High

174218

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.437

High

174236

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.437

High

174252

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.437

High

174253

STYK1
Tyrosine-protein kinase STYK1

1

20

High-throughput

0.437

High

174256

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.437

High

174267

HS12B
Heat shock 70 kDa protein 12B

1

1

High-throughput

0.437

High

174274

DJB11
DnaJ homolog subfamily B member 11

1

8

High-throughput

0.437

High

174261

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025