HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: NACC1 (Q96RE7)
Nucleus accumbens-associated protein 1 (NAC-1) (BTB/POZ domain-containing protein 14B)
Gene: NACC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37019189, 26673895
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 527
+	Hs
		173584 XPO1_HUMAN (1-1071): 0: 1022: 100.00		KLH20_HUMAN (4-271): 5.79e-68: 231: 16.18
+	Hs
		172804 XPO1_HUMAN (1-1071): 0: 1022: 100.00		KEAP1_HUMAN (3-260): 4.48e-58: 205: 14.66
+	Xl
		1205335 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		Q5HZR3_XENLA (3-271): 4.92e-60: 210: 15.22
+	Mm
		1021104 XPO1_MOUSE (1-1071): 0: 1019: 98.04		BACH1_MOUSE (2-367): 8.31e-43: 164: 18.83
+	Hs
		166468 XPO1_HUMAN (1-1071): 0: 1022: 100.00		BACH1_HUMAN (4-263): 1.11e-38: 152: 20.53
+	Hs
		173071 XPO1_HUMAN (1-1071): 0: 1022: 100.00		ZBTB2_HUMAN (7-117): 8.44e-11: 66.2: 34.82
+	Hs
		164668 TNPO2_HUMAN (33-1045): 7.81e-129: 415: 14.41		KLH20_HUMAN (4-271): 5.79e-68: 231: 16.18
+	Hs
		164659 TNPO2_HUMAN (33-1045): 7.81e-129: 415: 14.41		KLHL3_HUMAN (9-278): 4.32e-65: 223: 15.64
+	Hs
		164498 TNPO2_HUMAN (33-1045): 7.81e-129: 415: 14.41		KLHL2_HUMAN (9-322): 7.24e-63: 217: 15.46
+	Hs
		1200024 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		KLH26_HUMAN (7-314): 3.75e-60: 210: 16.35
+	Hs
		1121555 XPO7_HUMAN (23-1013): 1.49e-120: 398: 13.18		KEAP1_HUMAN (3-260): 4.48e-58: 205: 14.66
+	Hs
		164633 TNPO2_HUMAN (33-1045): 7.81e-129: 415: 14.41		Q9BS75_HUMAN (4-160): 1.82e-45: 161: 24.22
+	Mm
		1168708 XPO7_MOUSE (23-1013): 5.45e-120: 397: 13.01		ZBT48_MOUSE (9-278): 1.28e-37: 148: 21.96
+	Hs
		1134348 IMB1_HUMAN (27-908): 2.9e-90: 311: 11.32		ZBT18_HUMAN (7-218): 1.14e-45: 169: 22.12
+	Hs
		1134288 IMB1_HUMAN (27-908): 2.9e-90: 311: 11.32		ZBT34_HUMAN (2-291): 1.07e-44: 166: 25.17
+	Hs
		1134282 IMB1_HUMAN (27-908): 2.9e-90: 311: 11.32		ZBTB2_HUMAN (7-117): 8.44e-11: 66.2: 34.82