Interactor 1: NPHP1 (O15259)
Nephrocystin-1 (Juvenile nephronophthisis 1 protein)
Gene: NPHP1

Interactor 2: ACK1 (Q07912)
Activated CDC42 kinase 1 (ACK-1) (EC 2.7.10.2) (EC 2.7.11.1) (Tyrosine kinase non-receptor protein 2)
Gene: TNK2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.807

The method score is based on:

Property Details
Experiments 18477472, 21309750
Identification Methods two hybrid, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005912 - adherens junction
GO:0016020 - membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 732
Hs

1 1038
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024