HitPredict

Interactor 1: IPP2C (O14990)
Protein phosphatase inhibitor 2 family member C (PPP1R2 family member B) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9) (Type-1 protein phosphatase inhibitor 4) (I-4)
Gene: PPP1R2C

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 202 Hs			1 330
+	Hs
		834112 IPP2_HUMAN (1-198): 2.16e-76: 229: 41.29		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Mm
		968210 IPP2_MOUSE (1-199): 4.44e-76: 229: 41.87		PP1A_MOUSE (1-330): 0: 614: 99.70
+	Hs
		967804 IPP2B_HUMAN (1-198): 2.45e-74: 224: 40.80		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Hs
		786424 IPP2_HUMAN (1-198): 2.16e-76: 229: 41.29		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		174180 IPP2C_HUMAN (1-202): 4e-74: 224: 100.00		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		786670 IPP2B_HUMAN (1-198): 2.45e-74: 224: 40.80		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		834113 IPP2_HUMAN (1-198): 2.16e-76: 229: 41.29		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		174182 IPP2C_HUMAN (1-202): 4e-74: 224: 100.00		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		968345 IPP2B_HUMAN (1-198): 2.45e-74: 224: 40.80		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Dm
		68612 A8JNP7_DROME (1-158): 4.43e-49: 163: 29.11		PP11_DROME (4-330): 0: 573: 87.77
+	Dm
		68611 A8JNP7_DROME (1-158): 4.43e-49: 163: 29.11		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		68613 A8JNP7_DROME (1-158): 4.43e-49: 163: 29.11		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		68614 A8JNP7_DROME (1-158): 4.43e-49: 163: 29.11		PP13_DROME (5-304): 0: 550: 91.67
+	Dm
		873535 Q9V3C7_DROME (1-158): 2.15e-41: 140: 29.11		PP11_DROME (4-330): 0: 573: 87.77
+	Dm
		559073 Q9VJE7_DROME (34-162): 8.7e-45: 151: 25.58		PP12_DROME (7-304): 0: 553: 93.29
+	Ce
		876761 Q9N537_CAEEL (45-152): 3.77e-29: 108: 26.89		GLC7B_CAEEL (3-329): 0: 588: 90.52
+	Dm
		559057 Q9V3C7_DROME (1-158): 2.15e-41: 140: 29.11		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		873601 Q9V3C7_DROME (1-158): 2.15e-41: 140: 29.11		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		1051587 Q9V3C7_DROME (1-158): 2.15e-41: 140: 29.11		PP13_DROME (5-304): 0: 550: 91.67
+	Ce
		1176687 Q9N537_CAEEL (45-152): 3.77e-29: 108: 26.89		GLC7A_CAEEL (1-320): 0: 555: 84.57