HitPredict

Interactor 1: SPTC2 (O15270)
Serine palmitoyltransferase 2 (EC 2.3.1.50) (Long chain base biosynthesis protein 2) (LCB 2) (Long chain base biosynthesis protein 2a) (LCB2a) (Serine-palmitoyl-CoA transferase 2) (SPT 2)
Gene: SPTLC2

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 562 Hs			1 465
+	Hs
		226391 HEM1_HUMAN (31-542): 2.15e-170: 499: 24.18		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		174023 SPTC1_HUMAN (120-537): 9.36e-155: 453: 26.91		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		226066 KBL_HUMAN (133-536): 1.72e-148: 435: 31.61		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		270906 KBL_HUMAN (133-536): 1.72e-148: 435: 31.61		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	At
		791089 GSA1_ARATH (177-535): 3.06e-66: 224: 17.81		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17
+	At
		1091677 GSA2_ARATH (151-535): 5.35e-66: 223: 18.12		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17