HitPredict

Interactor 1: A8JNP7 (A8JNP7)
Inhibitor-2, isoform B
Gene: I-2

Interactor 2: PP12 (P12982)
Serine/threonine-protein phosphatase alpha-2 isoform (EC 3.1.3.16)
Gene: Pp1-87B

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.80	0.741

Property	Details
Experiments	14605208, 17007873, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Dm			1 302
+	Dm
		68612 A8JNP7_DROME (1-310): 2.34e-138: 395: 100.00		PP11_DROME (1-301): 0: 547: 96.68
+	Dm
		68614 A8JNP7_DROME (1-310): 2.34e-138: 395: 100.00		PP13_DROME (1-302): 0: 539: 93.71
+	Dm
		68613 A8JNP7_DROME (1-310): 2.34e-138: 395: 100.00		PP1B_DROME (1-302): 0: 530: 85.48
+	Dm
		559073 Q9VJE7_DROME (116-310): 9.17e-69: 217: 39.71		PP12_DROME (1-302): 0: 547: 100.00
+	Mm
		968210 IPP2_MOUSE (106-289): 1.28e-66: 209: 35.12		PP1A_MOUSE (2-301): 0: 550: 92.33
+	Hs
		786424 IPP2_HUMAN (106-289): 1.39e-64: 203: 33.82		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		834112 IPP2_HUMAN (106-289): 1.39e-64: 203: 33.82		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Hs
		786670 IPP2B_HUMAN (106-289): 4.55e-63: 200: 33.33		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		967804 IPP2B_HUMAN (106-289): 4.55e-63: 200: 33.33		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Dm
		559057 Q9V3C7_DROME (106-310): 3.48e-61: 195: 100.00		PP12_DROME (1-302): 0: 547: 100.00
+	Dm
		873535 Q9V3C7_DROME (106-310): 3.48e-61: 195: 100.00		PP11_DROME (1-301): 0: 547: 96.68
+	Hs
		834113 IPP2_HUMAN (106-289): 1.39e-64: 203: 33.82		PP1B_HUMAN (1-302): 0: 538: 87.79
+	Hs
		968345 IPP2B_HUMAN (106-289): 4.55e-63: 200: 33.33		PP1B_HUMAN (1-302): 0: 538: 87.79
+	Dm
		559035 Q4V424_DROME (135-310): 1.22e-57: 188: 21.93		PP12_DROME (1-302): 0: 547: 100.00
+	Dm
		1051587 Q9V3C7_DROME (106-310): 3.48e-61: 195: 100.00		PP13_DROME (1-302): 0: 539: 93.71
+	Hs
		174180 IPP2C_HUMAN (106-287): 2.53e-56: 182: 26.63		PP1G_HUMAN (3-301): 0: 549: 93.31
+	Hs
		174181 IPP2C_HUMAN (106-287): 2.53e-56: 182: 26.63		PP1A_HUMAN (2-301): 0: 549: 92.67
+	Dm
		873601 Q9V3C7_DROME (106-310): 3.48e-61: 195: 100.00		PP1B_DROME (1-302): 0: 530: 85.48
+	Dm
		873573 Q4V424_DROME (135-310): 1.22e-57: 188: 21.93		PP1B_DROME (1-302): 0: 530: 85.48
+	Dm
		1196426 Q4V424_DROME (135-310): 1.22e-57: 188: 21.93		Q8T0U6_DROME (17-302): 0: 516: 87.06