HitPredict

Interactor 1: IPP2 (P41236)
Protein phosphatase inhibitor 2 (IPP-2)
Gene: PPP1R2

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.983

Property	Details
Experiments	26186194, 27880917, 28514442, 27173435, 28330616, 29669786, 33961781, 22321011, 20826336, 25593058, 10807923
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, pull down, nuclear magnetic resonance, x ray scattering, molecular sieving, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation and 1 others more... filter binding
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	GO:0005977 - glycogen metabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 330
+	Hs
		967804 IPP2B_HUMAN (1-205): 1.51e-77: 232: 95.61		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Mm
		968210 IPP2_MOUSE (1-205): 6.74e-75: 226: 83.98		PP1A_MOUSE (1-330): 0: 614: 99.70
+	Hs
		786424 IPP2_HUMAN (1-205): 2.81e-78: 234: 100.00		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		786670 IPP2B_HUMAN (1-205): 1.51e-77: 232: 95.61		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		834113 IPP2_HUMAN (1-205): 2.81e-78: 234: 100.00		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		968345 IPP2B_HUMAN (1-205): 1.51e-77: 232: 95.61		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		174181 IPP2C_HUMAN (1-198): 1.05e-57: 182: 43.72		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Hs
		174180 IPP2C_HUMAN (1-198): 1.05e-57: 182: 43.72		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		174182 IPP2C_HUMAN (1-198): 1.05e-57: 182: 43.72		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Dm
		68612 A8JNP7_DROME (1-161): 9.82e-47: 157: 39.13		PP11_DROME (4-330): 0: 573: 87.77
+	Dm
		68611 A8JNP7_DROME (1-161): 9.82e-47: 157: 39.13		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		68613 A8JNP7_DROME (1-161): 9.82e-47: 157: 39.13		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		68614 A8JNP7_DROME (1-161): 9.82e-47: 157: 39.13		PP13_DROME (5-304): 0: 550: 91.67
+	Dm
		873535 Q9V3C7_DROME (1-161): 4.83e-39: 134: 39.13		PP11_DROME (4-330): 0: 573: 87.77
+	Dm
		559035 Q4V424_DROME (40-198): 3.79e-44: 150: 19.02		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		873573 Q4V424_DROME (40-198): 3.79e-44: 150: 19.02		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		559073 Q9VJE7_DROME (34-196): 1.76e-40: 141: 33.33		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		1196426 Q4V424_DROME (40-198): 3.79e-44: 150: 19.02		Q8T0U6_DROME (19-326): 0: 537: 84.42
+	Dm
		559057 Q9V3C7_DROME (1-161): 4.83e-39: 134: 39.13		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		873601 Q9V3C7_DROME (1-161): 4.83e-39: 134: 39.13		PP1B_DROME (6-326): 0: 551: 83.49