HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: OBSL1 (O75147)
Obscurin-like protein 1
Gene: OBSL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24711643, 31343991
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2390 Hs			1 1896
+	Hs
		224558 ACTN4_HUMAN (56-621): 3.27e-122: 412: 41.70		OBSL1_HUMAN (1-1896): 0: 1188: 100.00
+	Hs
		271972 UTRN_HUMAN (19-2384): 5.6e-86: 317: 14.27		OBSL1_HUMAN (1-1896): 0: 1188: 100.00
+	Hs
		271861 ACTN1_HUMAN (31-773): 4.46e-86: 305: 31.85		OBSL1_HUMAN (1-1896): 0: 1188: 100.00
+	Hs
		272093 DYST_HUMAN (1807-2150): 4.95e-11: 71: 13.35		OBSL1_HUMAN (1-1896): 0: 1188: 100.00
+	Hs
		249121 SPTB2_HUMAN (3-2390): 0: 708: 61.25		DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59
+	Hs
		224556 ACTN4_HUMAN (56-621): 3.27e-122: 412: 41.70		DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59
+	Hs
		249087 ACTN1_HUMAN (31-773): 4.46e-86: 305: 31.85		DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59
+	Dm
		612382 ACTN_DROME (51-762): 4.22e-95: 333: 31.94		Q7KQP6_DROME (3-424): 4.07e-39: 163: 19.32
+	Hs
		224763 ACTN4_HUMAN (56-621): 3.27e-122: 412: 41.70		TITIN_HUMAN (11-210): 2.79e-11: 71.6: 17.91
+	Hs
		773767 ACTN2_HUMAN (33-677): 1.68e-117: 398: 38.75		TITIN_HUMAN (11-210): 2.79e-11: 71.6: 17.91
+	Hs
		773740 ACTN2_HUMAN (33-677): 1.68e-117: 398: 38.75		MYPC2_HUMAN (1733-1894): 4.12e-09: 63.9: 25.90
+	Mm
		267106 Q91ZE6_MOUSE (305-2365): 9.67e-40: 165: 16.78		MYPC3_MOUSE (1-890): 5.94e-66: 248: 15.56
+	Mm
		97719 E9PX29_MOUSE (226-2365): 1.18e-39: 165: 16.32		MYPC3_MOUSE (1-890): 5.94e-66: 248: 15.56
+	Dm
		612396 ACTN_DROME (51-762): 4.22e-95: 333: 31.94		TITIN_DROME (1-100): 2.45e-10: 68.5: 22.77
+	Hs
		555729 ACTN1_HUMAN (31-773): 4.46e-86: 305: 31.85		TITIN_HUMAN (11-210): 2.79e-11: 71.6: 17.91
+	Hs
		249122 DYST_HUMAN (1807-2150): 4.95e-11: 71: 13.35		DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59
+	Hs
		249139 PLEC_HUMAN (231-967): 5.51e-11: 70.7: 10.58		DSCAM_HUMAN (1258-1895): 1.45e-72: 272: 16.59
+	Mm
		267089 DMD_MOUSE (228-1484): 5.66e-17: 90.7: 11.07		MYPC3_MOUSE (1-890): 5.94e-66: 248: 15.56
+	Hs
		1061541 ACTN3_HUMAN (808-1299): 8.63e-14: 79.5: 14.02		TITIN_HUMAN (11-210): 2.79e-11: 71.6: 17.91
+	Hs
		1040292 DYST_HUMAN (1807-2150): 4.95e-11: 71: 13.35		MYPC2_HUMAN (1733-1894): 4.12e-09: 63.9: 25.90