HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31586073, 36526897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 2390 Hs			1 1124
+	Hs
		1028888 SPTB2_HUMAN (3-2390): 0: 708: 61.25		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		540279 SPTB1_HUMAN (5-2119): 0: 644: 53.89		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		224804 ACTN4_HUMAN (56-621): 3.27e-122: 412: 41.70		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		773789 ACTN2_HUMAN (33-677): 1.68e-117: 398: 38.75		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		547486 DMD_HUMAN (54-2380): 6.08e-88: 324: 14.10		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		555766 ACTN1_HUMAN (31-773): 4.46e-86: 305: 31.85		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1117499 SPTN1_HUMAN (924-2356): 5.3e-53: 209: 19.70		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1431492 SPTN4_HUMAN (300-2365): 7.11e-39: 162: 16.81		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1061561 ACTN3_HUMAN (808-1299): 8.63e-14: 79.5: 14.02		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1040382 DYST_HUMAN (1807-2150): 4.95e-11: 71: 13.35		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1143276 PLEC_HUMAN (231-967): 5.51e-11: 70.7: 10.58		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		561587 SPTCA_DROME (1873-2224): 1.29e-12: 76.3: 16.76		ANLN_DROME (542-1112): 1.61e-160: 511: 29.84