Protein: SPTCA
Spectrin alpha chain

Gene: SPTCA, alpha-Spec
Organism: Drosophila melanogaster
Interactions: 76
UniProt ID: P13395

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561579

Q7KV70
Karst, isoform C

6

18

Small-scale

0.933

High

561568

SPTCB
Spectrin beta chain

5

19

Small-scale

0.898

High

561587

ANLN
Anillin

2

14

Small-scale

0.737

High

561566

CALM
Calmodulin

1

7

Small-scale

0.647

High

55670

A1Z9J2
Short stop, isoform C

1

19

Small-scale

0.618

High

81781

B5RJR1
Dachs, isoform D

1

20

High-throughput

0.618

High

386970

ACT2
Actin-42A

1

20

Small-scale

0.618

High

534342

ACT5
Actin-87E

1

20

Small-scale

0.618

High

534413

ACT1
Actin-5C

1

20

Small-scale

0.618

High

561565

ACT3
Actin-57B

1

20

Small-scale

0.618

High

561576

Q7K3H0
LD28067p

1

7

High-throughput

0.618

High

561606

Q9VR61
non-specific serine/threonine protein kinase

1

6

High-throughput

0.618

High

561580

LVA
Protein lava lamp

2

20

Small-scale

0.584

High

52499

A1Z6Z9
Dilute class unconventional myosin, isoform A

1

9

High-throughput

0.575

High

561562

SQH
Myosin regulatory light chain sqh

1

11

High-throughput

0.575

High

561569

HTS
Protein hu-li tai shao

1

6

High-throughput

0.575

High

561570

MY61F
Unconventional myosin IC

1

16

High-throughput

0.575

High

561591

FLNA
Filamin-A

1

19

High-throughput

0.575

High

561614

Q9VZQ3
Karst, isoform A

1

18

High-throughput

0.575

High

387023

ACT4
Actin, larval muscle

1

20

Small-scale

0.553

High

561567

ACT6
Actin, indirect flight muscle

1

20

Small-scale

0.553

High

561593

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

7

High-throughput

0.553

High

561597

SICK
Protein sickie

1

20

Small-scale

0.514

High

561588

Q9VBI4
Exocyst complex component 8

1

1

High-throughput

0.494

High

561608

EXOC7
Exocyst complex component 7

1

1

High-throughput

0.494

High

561571

Q23980
Beta-heavy-spectrin

1

19

High-throughput

0.492

High

57156

PTRO
Patronin

1

6

Small-scale

0.479

High

262718

TENM
Teneurin-m

1

6

Small-scale

0.479

High

561577

Q7KMQ6
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

13

High-throughput

0.479

High

561578

TERA
Transitional endoplasmic reticulum ATPase TER94

1

7

High-throughput

0.479

High

561581

Q8STB9
Dystroglycan 1

1

2

Small-scale

0.479

High

561590

Q9VCC9
LD23779p

1

20

High-throughput

0.479

High

561559

CLH
Clathrin heavy chain

1

0

High-throughput

0.458

High

561603

Q9VNU3
Cilia- and flagella-associated protein 45

1

20

High-throughput

0.457

High

69057

A8JRH3
FI20012p1

1

6

High-throughput

0.445

High

561563

PNUT
Protein peanut

1

4

High-throughput

0.445

High

561564

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.445

High

561572

FLII
Protein flightless-1

1

11

High-throughput

0.445

High

561575

Q7JVY0
Coronin

1

9

High-throughput

0.445

High

561594

TWF
Twinfilin

1

5

High-throughput

0.445

High

561598

EFHD2
EF-hand domain-containing protein D2 homolog

1

11

High-throughput

0.445

High

561615

Q9W016
Supervillin, isoform K

1

2

High-throughput

0.445

High

561616

CAPZA
F-actin-capping protein subunit alpha

1

11

High-throughput

0.445

High

52842

A1Z7C1
Mlh1, isoform A

1

5

High-throughput

0.439

High

120268

M9PD17
Gigas, isoform B

1

3

High-throughput

0.437

High

561573

SIMA
Protein similar

1

3

High-throughput

0.437

High

561586

FOXO
Forkhead box protein O

1

4

High-throughput

0.437

High

561592

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

8

High-throughput

0.437

High

561595

Q9VH62
LD44003p

1

20

High-throughput

0.437

High

561596

TEBPH
Cytosolic Prostaglandin E synthase

1

1

High-throughput

0.437

High

561605

Q9VR42
Serine/threonine-protein kinase RIO3

1

1

High-throughput

0.437

High

561610

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

2

High-throughput

0.437

High

561611

Q9VWJ6
FI03615p

1

5

High-throughput

0.437

High

561617

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.437

High

55151

A1Z934
SD19268p

1

4

High-throughput

0.417

High

561561

RL19
Large ribosomal subunit protein eL19

1

1

High-throughput

0.417

High

561582

Q8SXG7
tRNA selenocysteine-associated protein 1

1

3

High-throughput

0.417

High

561583

Q8T0N1
GH18717p

1

5

High-throughput

0.417

High

561600

Q9VL44
MIP05602p

1

2

High-throughput

0.417

High

561604

CPSF4
Cleavage and polyadenylation specificity factor subunit 4

1

1

High-throughput

0.417

High

561607

Q9VSB2
Uncharacterized protein, isoform A

1

10

High-throughput

0.417

High

561609

Q9VTX7
Eyegone, isoform A

1

4

High-throughput

0.417

High

561613

Q9VXQ0
Large ribosomal subunit protein uL3m

1

1

High-throughput

0.417

High

561557

MA205
205 kDa microtubule-associated protein

1

5

High-throughput

0.407

High

561558

PHB1
Prohibitin 1

1

2

High-throughput

0.407

High

561574

SARM1
NAD(+) hydrolase sarm1

1

9

High-throughput

0.407

High

561612

Q9VXN3
LD07988p

1

16

High-throughput

0.407

High

561602

Q9VML8
GH01721p

1

0

High-throughput

0.282

High

51888

PO210
Nuclear pore membrane glycoprotein 210

1

0

High-throughput

0.249

Low

561560

GLT
Glutactin

1

0

High-throughput

0.249

Low

561585

MESD
LDLR chaperone boca

1

0

High-throughput

0.249

Low

58433

A1ZBT3
Uncharacterized protein

1

0

High-throughput

0.238

Low

561584

Q8T8R6
AT31822p

1

0

High-throughput

0.238

Low

561589

Q9VBJ6
Uncharacterized protein

1

0

High-throughput

0.238

Low

561599

Q9VK23
FI16524p1

1

0

High-throughput

0.238

Low

561601

FGOP2
FGFR1 oncogene partner 2 homolog

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025