HitPredict

Interactor 1: TM9S1 (O15321)
Transmembrane 9 superfamily member 1 (MP70 protein family member) (hMP70)
Gene: TM9SF1

Interactor 2: S1PR1 (P21453)
Sphingosine 1-phosphate receptor 1 (S1P receptor 1) (S1P1) (Endothelial differentiation G-protein coupled receptor 1) (Sphingosine 1-phosphate receptor Edg-1) (S1P receptor Edg-1) (CD antigen CD363)
Gene: S1PR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 606 Hs			1 382
+	Hs
		175574 TM9S1_HUMAN (1-606): 0: 759: 100.00		LPAR1_HUMAN (23-342): 6.22e-89: 274: 38.51
+	Hs
		175551 TM9S1_HUMAN (1-606): 0: 759: 100.00		S1PR4_HUMAN (1-329): 2.24e-81: 255: 39.76
+	Hs
		175562 TM9S1_HUMAN (1-606): 0: 759: 100.00		OPRX_HUMAN (10-344): 2.01e-65: 214: 14.83
+	Hs
		1266797 TM9S4_HUMAN (9-606): 0: 679: 30.69		LPAR1_HUMAN (23-342): 6.22e-89: 274: 38.51
+	Hs
		1268661 TM9S3_HUMAN (33-606): 0: 664: 33.33		LPAR1_HUMAN (23-342): 6.22e-89: 274: 38.51
+	Hs
		328363 TM9S4_HUMAN (9-606): 0: 679: 30.69		S1PR4_HUMAN (1-329): 2.24e-81: 255: 39.76
+	Hs
		1268639 TM9S2_HUMAN (23-606): 0: 657: 28.19		LPAR1_HUMAN (23-342): 6.22e-89: 274: 38.51
+	Hs
		328397 TM9S3_HUMAN (33-606): 0: 664: 33.33		S1PR4_HUMAN (1-329): 2.24e-81: 255: 39.76
+	Hs
		598783 TM9S3_HUMAN (33-606): 0: 664: 33.33		S1PR1_HUMAN (1-382): 1.84e-80: 253: 100.00
+	Hs
		328378 TM9S2_HUMAN (23-606): 0: 657: 28.19		S1PR4_HUMAN (1-329): 2.24e-81: 255: 39.76
+	Hs
		429132 TM9S3_HUMAN (33-606): 0: 664: 33.33		ADRB2_HUMAN (14-347): 8.85e-70: 226: 17.08
+	Hs
		781105 TM9S3_HUMAN (33-606): 0: 664: 33.33		OPRX_HUMAN (10-344): 2.01e-65: 214: 14.83