HitPredict

Interactor 1: HMGB3 (O15347)
High mobility group protein B3 (High mobility group protein 2a) (HMG-2a) (High mobility group protein 4) (HMG-4)
Gene: HMGB3

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30554943
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 200 Hs			1 726
+	Hs
		996682 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		631411 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		BRD2_HUMAN (5-700): 1.46e-129: 405: 58.08
+	Hs
		996954 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		818600 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		449701 HMGB1_HUMAN (1-171): 1.02e-42: 144: 76.30		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		643336 HMGB2_HUMAN (1-184): 1.09e-40: 139: 69.52		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		996631 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		175732 HMGB3_HUMAN (13-180): 3.31e-46: 152: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		817978 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		243829 HMGB1_HUMAN (1-171): 1.02e-42: 144: 76.30		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		243964 HMGB2_HUMAN (1-184): 1.09e-40: 139: 69.52		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		999037 SOX7_HUMAN (3-102): 1.14e-20: 90.1: 23.00		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		876691 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		BRPF1_HUMAN (20-274): 6.8e-26: 116: 14.94
+	Hs
		244343 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		996791 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		PHIP_HUMAN (5-708): 5.37e-19: 94.5: 10.37
+	Hs
		996741 SSRP1_HUMAN (71-162): 2.49e-28: 112: 40.22		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		1311924 SOX7_HUMAN (3-102): 1.14e-20: 90.1: 23.00		CECR2_HUMAN (134-594): 1.39e-24: 112: 14.23
+	Hs
		818204 SOX2_HUMAN (3-94): 7.71e-24: 97.8: 27.17		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		1199196 SOX17_HUMAN (8-101): 1.64e-21: 92.4: 24.47		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		1199188 SOX7_HUMAN (3-102): 1.14e-20: 90.1: 23.00		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68