HitPredict

Interactor 1: SYNJ2 (O15056)
Synaptojanin-2 (EC 3.1.3.36) (Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2)
Gene: SYNJ2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.60	0.554

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1496 Hs			1 245
+	Hs
		176258 SYNJ2_HUMAN (1-1496): 0: 1390: 100.00		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		176250 SYNJ2_HUMAN (1-1496): 0: 1390: 100.00		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		176251 SYNJ2_HUMAN (1-1496): 0: 1390: 100.00		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		176262 SYNJ2_HUMAN (1-1496): 0: 1390: 100.00		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		176257 SYNJ2_HUMAN (1-1496): 0: 1390: 100.00		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		972154 SAC2_HUMAN (62-594): 3.32e-156: 505: 22.97		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		691557 SAC2_HUMAN (62-594): 3.32e-156: 505: 22.97		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		990890 SAC2_HUMAN (62-594): 3.32e-156: 505: 22.97		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		730372 SAC2_HUMAN (62-594): 3.32e-156: 505: 22.97		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		730972 SAC2_HUMAN (62-594): 3.32e-156: 505: 22.97		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		1049923 SAC2_HUMAN (62-594): 3.32e-156: 505: 22.97		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		967042 SAC2_HUMAN (62-594): 3.32e-156: 505: 22.97		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		187342 SHIP2_HUMAN (454-1318): 4.81e-139: 462: 19.82		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		730520 OCRL_HUMAN (488-964): 5.43e-129: 425: 27.93		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		215918 SYNJ1_HUMAN (1215-1496): 6.42e-10: 66.5: 10.64		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		215913 SYNJ1_HUMAN (1215-1496): 6.42e-10: 66.5: 10.64		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33