Protein: SAC2
Phosphatidylinositide phosphatase SAC2 (EC 3.1.3.25) (Inositol polyphosphate 5-phosphatase F) (Sac domain-containing inositol phosphatase 2) (Sac domain-containing phosphoinositide 4-phosphatase 2) (hSAC2)

Gene: SAC2, INPP5F
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q9Y2H2

Gene Ontology (top 5):
GO:0001921 - positive regulation of receptor recycling
GO:0005769 - early endosome
GO:0005905 - clathrin-coated pit
GO:0006661 - phosphatidylinositol biosynthetic process
GO:0008344 - adult locomotory behavior

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

631028

RAB4A
Ras-related protein Rab-4A

2

4

High-throughput

0.584

High

730372

1433B
14-3-3 protein beta/alpha

2

14

High-throughput

0.580

High

990890

1433Z
14-3-3 protein zeta/delta

2

14

High-throughput

0.580

High

976678

RB11A
Ras-related protein Rab-11A

2

0

High-throughput

0.559

High

1384158

ARRD3
Arrestin domain-containing protein 3

1

1

High-throughput

0.536

High

691557

1433T
14-3-3 protein theta

1

14

High-throughput

0.506

High

967042

1433G
14-3-3 protein gamma

1

14

High-throughput

0.506

High

972154

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.506

High

1049923

1433F
14-3-3 protein eta

1

14

High-throughput

0.506

High

189938

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

243332

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

562497

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

631574

RAB5A
Ras-related protein Rab-5A

1

3

High-throughput

0.479

High

901110

RAB5C
Ras-related protein Rab-5C

1

4

High-throughput

0.479

High

1110207

HDAC1
Histone deacetylase 1

1

3

High-throughput

0.479

High

1145181

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

1462778

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

791856

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

963550

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

0

Small-scale

0.458

High

247044

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.437

High

406812

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.437

High

459811

PROF1
Profilin-1

1

2

High-throughput

0.437

High

540765

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.437

High

590071

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.437

High

601507

RHOQ
Rho-related GTP-binding protein RhoQ

1

2

High-throughput

0.437

High

630668

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.437

High

696908

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

730972

1433S
14-3-3 protein sigma

1

14

High-throughput

0.437

High

769555

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

902148

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.437

High

956549

RAB2A
Ras-related protein Rab-2A

1

4

High-throughput

0.437

High

1151939

RHOH
Rho-related GTP-binding protein RhoH

1

3

High-throughput

0.437

High

1233590

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.437

High

1235350

STYK1
Tyrosine-protein kinase STYK1

1

3

High-throughput

0.437

High

1256164

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1333159

UN13C
Protein unc-13 homolog C

1

1

High-throughput

0.437

High

1358147

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.437

High

1362019

RFFL
E3 ubiquitin-protein ligase rififylin

1

2

Small-scale

0.437

High

1384487

PF21A
PHD finger protein 21A

1

1

High-throughput

0.437

High

1462004

ALK
ALK tyrosine kinase receptor

1

3

High-throughput

0.437

High

1490731

TRPV2
Transient receptor potential cation channel subfamily V member 2

1

1

Small-scale

0.417

High

219249

LTOR5
Ragulator complex protein LAMTOR5

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025