HitPredict

Interactor 1: ERC2 (O15083)
ERC protein 2
Gene: ERC2

Interactor 2: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34535262
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 957 Hs			1 245
+	Hs
		177111 ERC2_HUMAN (1-957): 2.57e-81: 285: 100.00		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Mm
		972251 ERC2_MOUSE (1-957): 3.29e-81: 285: 99.06		1433E_MOUSE (2-241): 9.95e-144: 403: 68.18
+	Hs
		177107 ERC2_HUMAN (1-957): 2.57e-81: 285: 100.00		1433B_HUMAN (1-242): 9.05e-140: 393: 87.60
+	Mm
		98050 DESP_MOUSE (209-907): 6.72e-68: 251: 19.44		1433E_MOUSE (2-241): 9.95e-144: 403: 68.18
+	Hs
		587614 DESP_HUMAN (209-907): 5.09e-67: 248: 19.01		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		587610 DESP_HUMAN (209-907): 5.09e-67: 248: 19.01		1433G_HUMAN (1-240): 2.38e-108: 314: 74.59
+	Hs
		587631 DESP_HUMAN (209-907): 5.09e-67: 248: 19.01		1433F_HUMAN (2-240): 1.27e-107: 312: 74.49
+	Hs
		776800 MYH11_HUMAN (314-953): 6.48e-32: 137: 13.11		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Hs
		776794 MYH11_HUMAN (314-953): 6.48e-32: 137: 13.11		1433E_HUMAN (2-241): 9.95e-144: 403: 68.18
+	Zm
		5605 A0A1D6DZK4_MAIZE (88-942): 1.36e-31: 136: 12.01		B6U284_MAIZE (1-241): 1.06e-142: 401: 63.27
+	Hs
		690788 MYH11_HUMAN (314-953): 6.48e-32: 137: 13.11		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		535929 MYH3_HUMAN (25-693): 1.29e-27: 123: 11.24		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Mm
		989976 MYH10_MOUSE (449-954): 5.86e-23: 108: 13.53		1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59
+	Mm
		990028 MYH9_MOUSE (17-634): 8.8e-23: 107: 11.31		1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59
+	Mm
		990044 RB6I2_MOUSE (43-686): 1.23e-22: 106: 9.41		1433Z_MOUSE (1-245): 3.49e-145: 407: 99.59
+	Hs
		556912 MYH7_HUMAN (7-558): 5.05e-22: 105: 11.57		1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00
+	Mm
		972305 RB6I2_MOUSE (43-686): 1.23e-22: 106: 9.41		1433E_MOUSE (2-241): 9.95e-144: 403: 68.18
+	Hs
		556897 MYH7_HUMAN (7-558): 5.05e-22: 105: 11.57		1433T_HUMAN (1-245): 2.61e-140: 395: 79.59
+	Hs
		776805 MYH11_HUMAN (314-953): 6.48e-32: 137: 13.11		1433F_HUMAN (2-240): 1.27e-107: 312: 74.49
+	Hs
		730420 MYH11_HUMAN (314-953): 6.48e-32: 137: 13.11		1433S_HUMAN (1-237): 8.31e-104: 302: 71.97