HitPredict

Interactor 1: STX7 (O15400)
Syntaxin-7
Gene: STX7

Interactor 2: VTI1B (Q9UEU0)
Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1)
Gene: VTI1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.948

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 12114520, 34079125, 35271311
Identification Methods affinity chromatography technology, pull down, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~V-SNARE_C
Common GO terms GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005765 - lysosomal membrane
GO:0006886 - intracellular protein transport
GO:0008021 - synaptic vesicle
and 7 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 261
Hs

1 232
+ Mm
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+ Dm
+ Ce
+ Hs
+ Dm
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+ At
+ At
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024