Protein: SCAM3
Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3)

Gene: SCAM3, SCAMP3
Organism: Homo sapiens
Interactions: 215
UniProt ID: O14828

Gene Ontology (top 5):
GO:0006892 - post-Golgi vesicle-mediated transport
GO:0015031 - protein transport
GO:0031625 - ubiquitin protein ligase binding
GO:0032588 - trans-Golgi network membrane
GO:0043231 - intracellular membrane-bounded organelle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

165561

RB11A
Ras-related protein Rab-11A

3

14

High-throughput

0.656

High

165480

SCAM2
Secretory carrier-associated membrane protein 2

2

5

High-throughput

0.628

High

165541

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

3

Small-scale

0.625

High

165548

RAB7A
Ras-related protein Rab-7a

2

16

High-throughput

0.611

High

165512

A4
Amyloid-beta precursor protein

2

3

Small-scale

0.585

High

165522

RFA2
Replication protein A 32 kDa subunit

2

1

High-throughput

0.584

High

165639

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

3

Small-scale

0.584

High

165594

A16L1
Autophagy-related protein 16-1

2

5

High-throughput

0.571

High

165532

CD27
CD27 antigen

2

4

High-throughput

0.549

High

165566

DLK1
Protein delta homolog 1

2

2

High-throughput

0.549

High

165552

TERA
Transitional endoplasmic reticulum ATPase

2

0

High-throughput

0.547

High

165542

YAP1
Transcriptional coactivator YAP1

2

6

Small-scale

0.542

High

165479

SCAM1
Secretory carrier-associated membrane protein 1

1

5

High-throughput

0.536

High

165491

TSN3
Tetraspanin-3

1

6

High-throughput

0.536

High

165495

TM63A
Mechanosensitive cation channel TMEM63A

1

1

High-throughput

0.536

High

165498

VAMP5
Vesicle-associated membrane protein 5

1

11

High-throughput

0.536

High

165503

TSN15
Tetraspanin-15

1

6

High-throughput

0.536

High

165518

LAMP1
Lysosome-associated membrane glycoprotein 1

1

8

High-throughput

0.536

High

165524

TSN8
Tetraspanin-8

1

6

High-throughput

0.536

High

165529

5NTD
5'-nucleotidase

1

1

High-throughput

0.536

High

165545

AGRE5
Adhesion G protein-coupled receptor E5

1

2

High-throughput

0.536

High

165563

RAB1A
Ras-related protein Rab-1A

1

16

High-throughput

0.536

High

165584

RB11B
Ras-related protein Rab-11B

1

19

High-throughput

0.536

High

165533

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

1

High-throughput

0.533

High

165537

RFA3
Replication protein A 14 kDa subunit

2

1

High-throughput

0.533

High

124990

KCNK1
Potassium channel subfamily K member 1

1

0

High-throughput

0.513

High

165508

GBA1
Lysosomal acid glucosylceramidase

1

0

High-throughput

0.513

High

165543

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

165600

S39A4
Zinc transporter ZIP4

1

0

High-throughput

0.513

High

165608

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.513

High

165619

S15A4
Solute carrier family 15 member 4

1

0

Small-scale

0.513

High

165630

NICA
Nicastrin

1

0

High-throughput

0.513

High

165635

IGSF8
Immunoglobulin superfamily member 8

1

0

High-throughput

0.513

High

165640

AP4AT
AP-4 complex accessory subunit Tepsin

1

0

High-throughput

0.513

High

165666

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.512

High

165655

DNJC5
DnaJ homolog subfamily C member 5

1

5

High-throughput

0.501

High

164878

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

4

High-throughput

0.489

High

165476

FFAR1
Free fatty acid receptor 1

1

8

High-throughput

0.489

High

165482

GP182
G-protein coupled receptor 182

1

7

High-throughput

0.489

High

165488

SNG1
Synaptogyrin-1

1

2

High-throughput

0.489

High

165499

RTN3
Reticulon-3

1

4

High-throughput

0.489

High

165500

LYPD3
Ly6/PLAUR domain-containing protein 3

1

1

High-throughput

0.489

High

165530

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

6

High-throughput

0.489

High

165531

FPR2
N-formyl peptide receptor 2

1

9

High-throughput

0.489

High

165534

EPHA2
Ephrin type-A receptor 2

1

4

High-throughput

0.489

High

165536

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

2

High-throughput

0.489

High

165540

P2RY2
P2Y purinoceptor 2

1

7

High-throughput

0.489

High

165572

TRDN
Triadin

1

1

High-throughput

0.489

High

165576

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.489

High

165581

P2RY6
P2Y purinoceptor 6

1

8

High-throughput

0.489

High

165588

MICA
MHC class I polypeptide-related sequence A

1

1

High-throughput

0.489

High

165591

TM63B
Mechanosensitive cation channel TMEM63B

1

1

High-throughput

0.489

High

165631

TM9S4
Transmembrane 9 superfamily member 4

1

1

High-throughput

0.489

High

165633

LPAR1
Lysophosphatidic acid receptor 1

1

9

High-throughput

0.489

High

165660

GPR35
G-protein coupled receptor 35

1

8

High-throughput

0.489

High

165672

CLC2D
C-type lectin domain family 2 member D

1

1

High-throughput

0.489

High

165676

GPR55
G-protein coupled receptor 55

1

13

High-throughput

0.489

High

165677

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

3

High-throughput

0.489

High

131575

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

3

Small-scale

0.481

High

165641

TS101
Tumor susceptibility gene 101 protein

1

0

Small-scale

0.480

High

165477

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

3

Small-scale

0.479

High

165478

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

165481

BET1
BET1 homolog

1

4

High-throughput

0.479

High

165483

STX7
Syntaxin-7

1

9

High-throughput

0.479

High

165489

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

165504

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.479

High

165505

RASN
GTPase NRas

1

20

High-throughput

0.479

High

165509

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

165510

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

165516

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

165520

LAMP2
Lysosome-associated membrane glycoprotein 2

1

8

High-throughput

0.479

High

165521

RAC2
Ras-related C3 botulinum toxin substrate 2

1

10

High-throughput

0.479

High

165523

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

165525

RAB3B
Ras-related protein Rab-3B

1

15

High-throughput

0.479

High

165526

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.479

High

165527

RAB5A
Ras-related protein Rab-5A

1

20

High-throughput

0.479

High

165535

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

165547

RAB5C
Ras-related protein Rab-5C

1

20

High-throughput

0.479

High

165549

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.479

High

165555

RAC3
Ras-related C3 botulinum toxin substrate 3

1

12

High-throughput

0.479

High

165556

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.479

High

165557

RAB2A
Ras-related protein Rab-2A

1

20

High-throughput

0.479

High

165558

RHOA
Transforming protein RhoA

1

14

High-throughput

0.479

High

165560

ARF6
ADP-ribosylation factor 6

1

9

High-throughput

0.479

High

165562

RHOB
Rho-related GTP-binding protein RhoB

1

14

High-throughput

0.479

High

165564

VAMP2
Vesicle-associated membrane protein 2

1

12

High-throughput

0.479

High

165571

STX4
Syntaxin-4

1

9

High-throughput

0.479

High

165582

RAB35
Ras-related protein Rab-35

1

10

High-throughput

0.479

High

165583

VAMP3
Vesicle-associated membrane protein 3

1

11

High-throughput

0.479

High

165597

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

165606

ATG9A
Autophagy-related protein 9A

1

2

High-throughput

0.479

High

165610

TAXB1
Tax1-binding protein 1

1

2

High-throughput

0.479

High

165612

PLD3
5'-3' exonuclease PLD3

1

1

High-throughput

0.479

High

165634

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

1

High-throughput

0.479

High

165637

OPTN
Optineurin

1

3

High-throughput

0.479

High

165650

RB33B
Ras-related protein Rab-33B

1

8

High-throughput

0.479

High

165652

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

Small-scale

0.479

High

165656

RHOJ
Rho-related GTP-binding protein RhoJ

1

14

High-throughput

0.479

High

165669

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

1

High-throughput

0.479

High

165673

LAMP3
Lysosome-associated membrane glycoprotein 3

1

8

High-throughput

0.479

High

155050

SOCS2
Suppressor of cytokine signaling 2

1

3

High-throughput

0.470

High

155978

SOCS6
Suppressor of cytokine signaling 6

1

3

High-throughput

0.470

High

165654

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.470

High

165513

JUN
Transcription factor Jun

1

0

High-throughput

0.458

High

165519

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

165538

BASI
Basigin

1

0

High-throughput

0.458

High

165569

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

165578

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

165592

CE350
Centrosome-associated protein 350

1

0

High-throughput

0.458

High

165593

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

165648

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

High-throughput

0.458

High

165651

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

165670

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

165671

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

165554

CD81
CD81 antigen

1

5

High-throughput

0.445

High

165568

LAT1
Large neutral amino acids transporter small subunit 1

1

5

High-throughput

0.445

High

165629

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

165643

S12A9
Solute carrier family 12 member 9

1

6

High-throughput

0.445

High

104842

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

126363

RHOD
Rho-related GTP-binding protein RhoD

1

16

High-throughput

0.437

High

139761

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

1

High-throughput

0.437

High

164171

NRP1
Neuropilin-1

1

1

High-throughput

0.437

High

165486

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.437

High

165493

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

165496

RIMB1
Peripheral-type benzodiazepine receptor-associated protein 1

1

1

High-throughput

0.437

High

165497

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

165501

DIRA3
GTP-binding protein Di-Ras3

1

15

High-throughput

0.437

High

165506

RASH
GTPase HRas

1

20

High-throughput

0.437

High

165507

RASK
GTPase KRas

1

20

High-throughput

0.437

High

165511

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

165528

ATP4A
Potassium-transporting ATPase alpha chain 1

1

3

Small-scale

0.437

High

165544

SC6A8
Sodium- and chloride-dependent creatine transporter 1

1

3

Small-scale

0.437

High

165550

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.437

High

165565

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

165567

IFM3
Interferon-induced transmembrane protein 3

1

4

High-throughput

0.437

High

165577

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.437

High

165587

DUS7
Dual specificity protein phosphatase 7

1

1

High-throughput

0.437

High

165589

MIDN
Midnolin

1

2

High-throughput

0.437

High

165596

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

165601

LMBRL
Protein LMBR1L

1

2

High-throughput

0.437

High

165604

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

165609

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.437

High

165611

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

165614

MA7D3
MAP7 domain-containing protein 3

1

3

High-throughput

0.437

High

165616

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.437

High

165622

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.437

High

165644

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

1

High-throughput

0.437

High

165645

GPR61
G-protein coupled receptor 61

1

1

High-throughput

0.437

High

165657

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

165662

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.437

High

165665

ELOV5
Very long chain fatty acid elongase 5

1

2

High-throughput

0.437

High

165514

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.426

High

165590

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

165595

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

0

High-throughput

0.426

High

165664

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

Small-scale

0.426

High

97206

E9PS44
Interferon induced transmembrane protein 3

1

4

High-throughput

0.407

High

165485

CTR4
Cationic amino acid transporter 4

1

5

High-throughput

0.407

High

165492

S19A2
Thiamine transporter 1

1

4

High-throughput

0.407

High

165517

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.407

High

165551

CTR2
Cationic amino acid transporter 2

1

5

High-throughput

0.407

High

165575

CTBP1
C-terminal-binding protein 1

1

1

High-throughput

0.407

High

165605

NIPA1
Magnesium transporter NIPA1

1

1

High-throughput

0.407

High

165613

S22A9
Organic anion transporter 7

1

1

High-throughput

0.407

High

165620

MFSD9
Major facilitator superfamily domain-containing protein 9

1

5

High-throughput

0.407

High

165623

VGLU3
Vesicular glutamate transporter 3

1

4

High-throughput

0.407

High

165624

DIK2A
Divergent protein kinase domain 2A

1

1

Small-scale

0.407

High

165646

S19A3
Thiamine transporter 2

1

4

High-throughput

0.407

High

165668

VGLU2
Vesicular glutamate transporter 2

1

4

High-throughput

0.407

High

60689

F234B
Protein FAM234B

1

0

High-throughput

0.279

Low

165487

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.279

Low

165494

ST17B
Serine/threonine-protein kinase 17B

1

0

High-throughput

0.279

Low

165502

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.279

Low

165515

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.279

Low

165573

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.279

Low

165585

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

165599

CDC73
Parafibromin

1

0

High-throughput

0.279

Low

165602

MBOA1
Membrane-bound glycerophospholipid O-acyltransferase 1

1

0

High-throughput

0.279

Low

165615

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.279

Low

165617

LRC25
Leucine-rich repeat-containing protein 25

1

0

High-throughput

0.279

Low

165618

IT70B
Intraflagellar transport protein 70B

1

0

High-throughput

0.279

Low

165626

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.279

Low

165627

GPBAR
G-protein coupled bile acid receptor 1

1

0

High-throughput

0.279

Low

165638

PGAP3
GPI-specific phospholipase A2-like PGAP3

1

0

High-throughput

0.279

Low

165663

HAUS2
HAUS augmin-like complex subunit 2

1

0

High-throughput

0.279

Low

165675

LTOR2
Ragulator complex protein LAMTOR2

1

0

High-throughput

0.279

Low

839

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.253

Low

47929

RBM47
RNA-binding protein 47

1

0

High-throughput

0.249

Low

165484

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

165490

ONEC3
One cut domain family member 3

1

0

High-throughput

0.249

Low

165539

OPRD
Delta-type opioid receptor

1

0

Small-scale

0.249

Low

165546

CDK7
Cyclin-dependent kinase 7

1

0

High-throughput

0.249

Low

165553

KLF3
Krueppel-like factor 3

1

0

High-throughput

0.249

Low

165559

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.249

Low

165570

DHX9
ATP-dependent RNA helicase A

1

0

Small-scale

0.249

Low

165574

CLN3
Battenin

1

0

Small-scale

0.249

Low

165579

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

0

High-throughput

0.249

Low

165580

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.249

Low

165586

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

165603

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.249

Low

165607

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

165625

I17RD
Interleukin-17 receptor D

1

0

High-throughput

0.249

Low

165628

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.249

Low

165632

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low

165636

OTUL
Ubiquitin thioesterase otulin

1

0

Small-scale

0.249

Low

165642

RN126
E3 ubiquitin-protein ligase RNF126

1

0

Small-scale

0.249

Low

165649

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

165653

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.249

Low

165658

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

165659

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.249

Low

165661

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

165667

BTBD7
BTB/POZ domain-containing protein 7

1

0

High-throughput

0.249

Low

165674

INVS
Inversin

1

0

High-throughput

0.249

Low

165598

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

165621

S38A9
Neutral amino acid transporter 9

1

0

High-throughput

0.232

Low

165647

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025