HitPredict

Interactor 1: SOCS1 (O15524)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)
Gene: SOCS1

Interactor 2: CRKL (P46109)
Crk-like protein
Gene: CRKL

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 25814554, 29991678, unassigned1126
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~SH2, SH2~SH3_1, SH2~SH3_2, SH2~SOCS_box
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0035556 - intracellular signal transduction
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 211
Hs

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Last updated: 15 Jul 2024