Protein: CDCA3
Cell division cycle-associated protein 3 (Gene-rich cluster protein C8) (Trigger of mitotic entry protein 1) (TOME-1)

Gene: CDCA3
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q99618

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005912 - adherens junction
GO:0016567 - protein ubiquitination
GO:0051301 - cell division

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1090875

TRAF2
TNF receptor-associated factor 2

4

1

High-throughput

0.705

High

1405942

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

10

3

High-throughput

0.692

High

158586

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

9

3

High-throughput

0.690

High

1405963

FZR1
Fizzy-related protein homolog

5

0

Small-scale

0.684

High

375871

RASK
GTPase KRas

4

5

High-throughput

0.676

High

1093934

TRAF1
TNF receptor-associated factor 1

3

1

High-throughput

0.675

High

181728

CTDSL
CTD small phosphatase-like protein

6

3

High-throughput

0.673

High

992314

SKP1
S-phase kinase-associated protein 1

3

0

Small-scale

0.646

High

299349

FLOT1
Flotillin-1

2

1

High-throughput

0.611

High

1405939

CHM4A
Charged multivesicular body protein 4a

2

0

High-throughput

0.602

High

637113

VATC1
V-type proton ATPase subunit C 1

2

0

High-throughput

0.585

High

374157

RASN
GTPase NRas

2

5

High-throughput

0.584

High

374874

RASH
GTPase HRas

2

3

High-throughput

0.584

High

540639

LAMP1
Lysosome-associated membrane glycoprotein 1

2

2

High-throughput

0.584

High

978246

RHOB
Rho-related GTP-binding protein RhoB

2

8

High-throughput

0.584

High

348679

AIFM1
Apoptosis-inducing factor 1, mitochondrial

2

0

High-throughput

0.559

High

560065

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

2

0

High-throughput

0.559

High

951375

SC61B
Protein transport protein Sec61 subunit beta

2

0

High-throughput

0.559

High

337968

CNEP1
CTD nuclear envelope phosphatase 1

2

3

High-throughput

0.558

High

1112674

CUL1
Cullin-1

1

0

Small-scale

0.537

High

1124896

FLOT2
Flotillin-2

1

1

High-throughput

0.536

High

1405943

BC11A
BCL11 transcription factor A

1

0

High-throughput

0.518

High

718617

CDC27
Cell division cycle protein 27 homolog

1

0

High-throughput

0.513

High

1142260

CD5R1
Cyclin-dependent kinase 5 activator 1

1

0

High-throughput

0.513

High

1405941

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.513

High

1328444

S2541
Mitochondrial carrier protein SCaMC-3L

1

1

High-throughput

0.489

High

422965

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

508496

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

719034

WEE1
Wee1-like protein kinase

1

0

Small-scale

0.480

High

48758

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.479

High

126765

RHOD
Rho-related GTP-binding protein RhoD

1

10

High-throughput

0.479

High

181818

EPHB6
Ephrin type-B receptor 6

1

8

High-throughput

0.479

High

363761

EGFR
Epidermal growth factor receptor

1

6

High-throughput

0.479

High

440186

LCK
Tyrosine-protein kinase Lck

1

1

High-throughput

0.479

High

463725

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.479

High

466430

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

541653

FGFR1
Fibroblast growth factor receptor 1

1

10

High-throughput

0.479

High

593477

PGFRA
Platelet-derived growth factor receptor alpha

1

6

High-throughput

0.479

High

612290

ARF4
ADP-ribosylation factor 4

1

1

High-throughput

0.479

High

631433

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.479

High

710654

EPHA3
Ephrin type-A receptor 3

1

8

High-throughput

0.479

High

710883

EPHB2
Ephrin type-B receptor 2

1

7

High-throughput

0.479

High

901519

RAB7A
Ras-related protein Rab-7a

1

3

High-throughput

0.479

High

902028

RAB9A
Ras-related protein Rab-9A

1

3

High-throughput

0.479

High

953633

RAC3
Ras-related C3 botulinum toxin substrate 3

1

7

High-throughput

0.479

High

955514

CDC42
Cell division control protein 42 homolog

1

8

High-throughput

0.479

High

956456

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

962417

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

962815

RND3
Rho-related GTP-binding protein RhoE

1

9

High-throughput

0.479

High

975197

ARF6
ADP-ribosylation factor 6

1

1

High-throughput

0.479

High

988645

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

High-throughput

0.479

High

1015708

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

1087256

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

1145077

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.479

High

1146464

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.479

High

1159530

NTRK2
BDNF/NT-3 growth factors receptor

1

14

High-throughput

0.479

High

1270958

RHOU
Rho-related GTP-binding protein RhoU

1

9

High-throughput

0.479

High

1287420

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

High-throughput

0.479

High

1405946

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

1405951

RHOF
Rho-related GTP-binding protein RhoF

1

9

High-throughput

0.479

High

164424

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

226180

STX6
Syntaxin-6

1

0

High-throughput

0.458

High

347884

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

556302

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

582933

EZRI
Ezrin

1

0

High-throughput

0.458

High

605794

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

715735

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

719659

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

0

High-throughput

0.458

High

894999

EMD
Emerin

1

0

High-throughput

0.458

High

936431

AFAD
Afadin

1

0

High-throughput

0.458

High

976510

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

986664

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1004177

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

1125622

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

0

High-throughput

0.458

High

1227331

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.458

High

1229050

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

1366534

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1405949

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

1405958

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

1405961

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1405967

FIS1
Mitochondrial fission 1 protein

1

0

High-throughput

0.458

High

1405968

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.458

High

720309

UFO
Tyrosine-protein kinase receptor UFO

1

9

High-throughput

0.457

High

189794

STX7
Syntaxin-7

1

1

High-throughput

0.437

High

341132

DIRA3
GTP-binding protein Di-Ras3

1

1

High-throughput

0.437

High

412498

NTRK1
High affinity nerve growth factor receptor

1

14

High-throughput

0.437

High

439836

INSR
Insulin receptor

1

10

High-throughput

0.437

High

464040

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

8

High-throughput

0.437

High

465624

IGF1R
Insulin-like growth factor 1 receptor

1

12

High-throughput

0.437

High

484209

PGFRB
Platelet-derived growth factor receptor beta

1

8

High-throughput

0.437

High

560493

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.437

High

562346

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.437

High

601418

RHOQ
Rho-related GTP-binding protein RhoQ

1

8

High-throughput

0.437

High

604172

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.437

High

630615

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.437

High

630948

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.437

High

641244

FGFR2
Fibroblast growth factor receptor 2

1

13

High-throughput

0.437

High

648641

FGFR4
Fibroblast growth factor receptor 4

1

11

High-throughput

0.437

High

711932

LTK
Leukocyte tyrosine kinase receptor

1

12

High-throughput

0.437

High

901003

RAB5C
Ras-related protein Rab-5C

1

2

High-throughput

0.437

High

931887

EPHA5
Ephrin type-A receptor 5

1

9

High-throughput

0.437

High

1031515

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.437

High

1034328

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

12

High-throughput

0.437

High

1055083

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

10

High-throughput

0.437

High

1058614

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.437

High

1063011

DDR1
Epithelial discoidin domain-containing receptor 1

1

9

High-throughput

0.437

High

1147415

EPHA7
Ephrin type-A receptor 7

1

7

High-throughput

0.437

High

1151838

RHOH
Rho-related GTP-binding protein RhoH

1

8

High-throughput

0.437

High

1157043

NTRK3
NT-3 growth factor receptor

1

11

High-throughput

0.437

High

1235319

STYK1
Tyrosine-protein kinase STYK1

1

8

High-throughput

0.437

High

1312232

MIRO2
Mitochondrial Rho GTPase 2

1

12

High-throughput

0.437

High

1322962

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.437

High

1326507

ARL14
ADP-ribosylation factor-like protein 14

1

2

High-throughput

0.437

High

1405937

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.437

High

1405944

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.437

High

1405947

RHOJ
Rho-related GTP-binding protein RhoJ

1

8

High-throughput

0.437

High

1405956

ARL15
ADP-ribosylation factor-like protein 15

1

3

High-throughput

0.437

High

1405960

DNJ5B
DnaJ homolog subfamily C member 5B

1

1

High-throughput

0.437

High

1405964

ALK
ALK tyrosine kinase receptor

1

11

High-throughput

0.437

High

1405966

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.437

High

1405971

ARL5A
ADP-ribosylation factor-like protein 5A

1

2

High-throughput

0.437

High

1405972

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.437

High

1105166

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.426

High

1234919

PKHA7
Pleckstrin homology domain-containing family A member 7

1

0

High-throughput

0.426

High

1405969

SRPRB
Signal recognition particle receptor subunit beta

1

2

High-throughput

0.407

High

733421

CCR1
C-C chemokine receptor type 1

2

0

High-throughput

0.328

High

1293530

CIR1
Corepressor interacting with RBPJ 1

2

0

High-throughput

0.328

High

1402968

CP2S1
Cytochrome P450 2S1

2

0

High-throughput

0.328

High

1405965

PCDGK
Protocadherin gamma-C3

2

0

High-throughput

0.328

High

1405950

SFXN1
Sideroflexin-1

2

0

High-throughput

0.305

High

616797

SDC1
Syndecan-1

1

0

High-throughput

0.279

Low

1257573

TF2H5
General transcription factor IIH subunit 5

1

0

High-throughput

0.279

Low

1338675

T185A
Transmembrane protein 185A

1

0

High-throughput

0.279

Low

1391279

CERS2
Ceramide synthase 2

1

0

High-throughput

0.279

Low

1405948

GSX1
GS homeobox 1

1

0

High-throughput

0.279

Low

1405962

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

0

High-throughput

0.279

Low

1405970

MYH4
Myosin-4

1

0

High-throughput

0.279

Low

139970

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

166989

MGST3
Glutathione S-transferase 3, mitochondrial

1

0

High-throughput

0.249

Low

218673

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

279873

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.249

Low

292205

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.249

Low

296289

SCO1
Protein SCO1 homolog, mitochondrial

1

0

High-throughput

0.249

Low

327422

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.249

Low

418383

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

580681

AMPN
Aminopeptidase N

1

0

High-throughput

0.249

Low

699040

CALX
Calnexin

1

0

High-throughput

0.249

Low

837806

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

845773

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.249

Low

1027151

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

1041242

CAV1
Caveolin-1

1

0

High-throughput

0.249

Low

1081826

LTOR4
Ragulator complex protein LAMTOR4

1

0

High-throughput

0.249

Low

1111674

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

1147668

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low

1159819

OCLN
Occludin

1

0

High-throughput

0.249

Low

1233442

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1276287

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

1278086

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.249

Low

1286883

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low

1293124

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1331445

VA0D2
V-type proton ATPase subunit d 2

1

0

High-throughput

0.249

Low

1381944

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.249

Low

1383028

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.249

Low

1394047

COX14
Cytochrome c oxidase assembly protein COX14

1

0

High-throughput

0.249

Low

1401210

PANX1
Pannexin-1

1

0

High-throughput

0.249

Low

1403762

RMD3
Regulator of microtubule dynamics protein 3

1

0

High-throughput

0.249

Low

1404170

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

1405936

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

0

High-throughput

0.249

Low

1405938

DERL1
Derlin-1

1

0

High-throughput

0.249

Low

1405940

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

1405945

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

1405952

PLRKT
Plasminogen receptor

1

0

High-throughput

0.249

Low

1405953

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.249

Low

1405954

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.249

Low

1405955

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low

1405957

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.249

Low

1405959

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.249

Low

346776

CER1
Cerberus

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025