HitPredict

Interactor 1: RAB6 (O18334)
Ras-related protein Rab6 (Protein warthog)
Gene: RAB6

Interactor 2: X2JE40 (X2JE40)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: Rok

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	15710747
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~Ras, Ras~Rho_Binding
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 208 Dm			1 1374
+	Dm
		185650 RAB6_DROME (1-208): 7.45e-88: 258: 100.00		Q9VXE3_DROME (1-1370): 0: 813: 99.56
+	Dm
		1358762 RAB5_DROME (12-206): 1.51e-49: 162: 41.03		X2JE40_DROME (1-1374): 0: 821: 100.00
+	Hs
		254466 RB11A_HUMAN (1-207): 1.84e-87: 258: 30.84		ROCK2_HUMAN (1-1352): 0: 647: 42.33
+	Hs
		592236 RAB5A_HUMAN (7-174): 1.11e-48: 159: 44.64		ROCK1_HUMAN (19-1355): 0: 689: 43.33
+	Hs
		148636 RAB1A_HUMAN (1-207): 1.65e-92: 270: 36.23		CTRO_HUMAN (24-1316): 5.98e-137: 466: 20.47
+	Hs
		149274 RAB1B_HUMAN (7-207): 7.23e-90: 263: 35.82		CTRO_HUMAN (24-1316): 5.98e-137: 466: 20.47
+	Dm
		116371 RAB6_DROME (1-208): 7.45e-88: 258: 100.00		M9PI41_DROME (5-1305): 7.4e-135: 458: 17.98
+	At
		221736 RAA1E_ARATH (1-207): 6.36e-86: 254: 32.56		KIN10_ARATH (86-496): 2.41e-123: 394: 22.03
+	Hs
		148389 RAB5A_HUMAN (7-174): 1.11e-48: 159: 44.64		CTRO_HUMAN (24-1316): 5.98e-137: 466: 20.47
+	Hs
		914081 RB11A_HUMAN (1-207): 1.84e-87: 258: 30.84		STK38_HUMAN (75-402): 6.1e-76: 261: 40.22
+	Hs
		914124 RB11A_HUMAN (1-207): 1.84e-87: 258: 30.84		MRCKA_HUMAN (654-1306): 2.09e-43: 175: 12.50
+	Hs
		592267 RAB5A_HUMAN (7-174): 1.11e-48: 159: 44.64		STK38_HUMAN (75-402): 6.1e-76: 261: 40.22
+	Dm
		1358706 RAB5_DROME (12-206): 1.51e-49: 162: 41.03		WARTS_DROME (17-386): 1.13e-63: 239: 35.02