HitPredict

Interactor 1: HDA19 (O22446)
Histone deacetylase 19 (AtHD1) (HD) (EC 3.5.1.98)
Gene: HDA19

Interactor 2: SNL1 (Q9SRH9)
Paired amphipathic helix protein Sin3-like 1
Gene: SNL1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	23371947
Identification Methods	two hybrid, protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000118 - histone deacetylase complex GO:0005634 - nucleus GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 At			1 1372
+	At
		186875 HDA19_ARATH (1-501): 0: 671: 100.00		SNL3_ARATH (46-1371): 0: 1287: 45.58
+	Mm
		140278 HDAC1_MOUSE (12-451): 0: 629: 61.77		SIN3B_MOUSE (635-1370): 1.56e-159: 511: 16.22
+	Hs
		257815 HDAC2_HUMAN (8-494): 0: 634: 56.03		SIN3B_HUMAN (670-1371): 1.9e-143: 469: 15.43
+	Hs
		257779 HDAC1_HUMAN (12-451): 0: 626: 61.31		SIN3B_HUMAN (670-1371): 1.9e-143: 469: 15.43
+	Mm
		1143586 HDAC4_MOUSE (7-420): 4.02e-132: 410: 22.00		SIN3B_MOUSE (635-1370): 1.56e-159: 511: 16.22
+	Mm
		140313 HDAC1_MOUSE (12-451): 0: 629: 61.77		GON4L_MOUSE (58-331): 3.33e-46: 185: 17.19
+	Ce
		60834 HDA1_CAEEL (1-455): 0: 584: 55.87		SIN3_CAEEL (121-469): 3.22e-25: 116: 14.45
+	Hs
		1270395 HDAC2_HUMAN (8-494): 0: 634: 56.03		SIN3A_HUMAN (24-142): 3.59e-09: 63.8: 22.39
+	Mm
		936394 HDAC2_MOUSE (8-494): 0: 632: 56.24		SIN3A_MOUSE (24-142): 4.11e-09: 63.4: 22.39
+	Mm
		140270 HDAC1_MOUSE (12-451): 0: 629: 61.77		SIN3A_MOUSE (24-142): 4.11e-09: 63.4: 22.39
+	Hs
		1038650 HDAC1_HUMAN (12-451): 0: 626: 61.31		SIN3A_HUMAN (24-142): 3.59e-09: 63.8: 22.39
+	Sc
		609058 RPD3_YEAST (16-433): 0: 577: 54.31		SIN3_YEAST (137-405): 5.28e-23: 109: 15.56
+	Dm
		1137165 HDAC1_DROME (12-495): 0: 610: 54.43		Q5U0Y0_DROME (125-204): 1.63e-11: 71.5: 24.69
+	Dm
		184384 HDAC1_DROME (12-495): 0: 610: 54.43		O17142_DROME (125-204): 1.44e-11: 71.5: 24.69
+	Ce
		60810 G5ECH0_CAEEL (13-451): 0: 563: 54.71		SIN3_CAEEL (121-469): 3.22e-25: 116: 14.45
+	Sp
		140530 PHD1_SCHPO (14-420): 0: 530: 53.66		PST3_SCHPO (800-1372): 2.94e-23: 109: 12.48
+	Sp
		140653 PHD1_SCHPO (14-420): 0: 530: 53.66		PST1_SCHPO (12-119): 3.35e-09: 63.8: 19.20
+	Hs
		880810 HDAC4_HUMAN (7-420): 7.05e-130: 405: 20.63		SIN3A_HUMAN (24-142): 3.59e-09: 63.8: 22.39
+	Sc
		609122 HDA1_YEAST (18-338): 3.67e-116: 359: 24.06		SIN3_YEAST (137-405): 5.28e-23: 109: 15.56
+	Dm
		1137160 Q86NK9_DROME (15-333): 6.46e-88: 293: 22.36		Q5U0Y0_DROME (125-204): 1.63e-11: 71.5: 24.69