Protein: GPR37
Prosaposin receptor GPR37 (Endothelin B receptor-like protein 1) (ETBR-LP-1) (G-protein coupled receptor 37) (Parkin-associated endothelin receptor-like receptor) (PAELR)

Gene: GPR37
Organism: Homo sapiens
Interactions: 92
UniProt ID: O15354

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0004930 - G protein-coupled receptor activity
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

186874

ADRB2
Beta-2 adrenergic receptor

2

17

Small-scale

0.821

High

186886

AA2AR
Adenosine receptor A2a

1

17

High-throughput

0.772

High

186906

5HT4R
5-hydroxytryptamine receptor 4

1

17

High-throughput

0.752

High

186926

WDFY1
WD repeat and FYVE domain-containing protein 1

2

5

High-throughput

0.726

High

186867

GPR37
Prosaposin receptor GPR37

1

17

High-throughput

0.698

High

186878

DRD2
D(2) dopamine receptor

1

19

High-throughput

0.698

High

186885

5HT2C
5-hydroxytryptamine receptor 2C

1

18

High-throughput

0.698

High

186891

ADA1A
Alpha-1A adrenergic receptor

1

18

High-throughput

0.698

High

186904

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

17

High-throughput

0.698

High

186907

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.698

High

186944

LT4R2
Leukotriene B4 receptor 2

1

17

High-throughput

0.698

High

186888

ARRB2
Beta-arrestin-2

1

13

High-throughput

0.691

High

186923

SYVN1
E3 ubiquitin-protein ligase synoviolin

3

3

Small-scale

0.683

High

186869

PRKN
E3 ubiquitin-protein ligase parkin

3

2

Small-scale

0.672

High

186872

ATE1
Arginyl-tRNA--protein transferase 1

2

0

High-throughput

0.602

High

186951

NXF1
Nuclear RNA export factor 1

2

0

High-throughput

0.602

High

186875

4F2
Amino acid transporter heavy chain SLC3A2

1

3

High-throughput

0.592

High

186871

YIF1A
Protein YIF1A

1

2

High-throughput

0.582

High

186912

YIF1B
Protein YIF1B

1

2

High-throughput

0.582

High

186940

TTYH1
Protein tweety homolog 1

1

3

High-throughput

0.582

High

186950

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

1

High-throughput

0.582

High

186919

FA2H
Fatty acid 2-hydroxylase

1

5

High-throughput

0.568

High

186893

GLP1R
Glucagon-like peptide 1 receptor

1

8

Small-scale

0.552

High

186945

PICK1
PRKCA-binding protein

1

0

Small-scale

0.549

High

155224

AGRB1
Adhesion G protein-coupled receptor B1

1

9

High-throughput

0.541

High

186870

TM63A
Mechanosensitive cation channel TMEM63A

1

1

High-throughput

0.541

High

186876

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.541

High

186879

ENPL
Endoplasmin

1

1

High-throughput

0.541

High

186895

HDGF
Hepatoma-derived growth factor

1

1

High-throughput

0.541

High

186896

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

1

High-throughput

0.541

High

186899

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.541

High

186902

CNTN1
Contactin-1

1

2

High-throughput

0.541

High

186903

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

1

High-throughput

0.541

High

186905

TMED1
Transmembrane emp24 domain-containing protein 1

1

1

High-throughput

0.541

High

186915

WLS
Protein wntless homolog

1

4

High-throughput

0.541

High

186931

S41A3
Solute carrier family 41 member 3

1

1

High-throughput

0.541

High

186934

TTYH2
Protein tweety homolog 2

1

3

High-throughput

0.541

High

186941

GHITM
Growth hormone-inducible transmembrane protein

1

5

High-throughput

0.541

High

186943

ZDH11
Palmitoyltransferase ZDHHC11

1

3

High-throughput

0.541

High

186949

JKAMP
JNK1/MAPK8-associated membrane protein

1

2

High-throughput

0.541

High

186954

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

1

High-throughput

0.541

High

186881

PTPRD
Receptor-type tyrosine-protein phosphatase delta

1

5

High-throughput

0.536

High

186933

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

4

High-throughput

0.536

High

186947

T161A
Transmembrane protein 161A

1

1

High-throughput

0.532

High

186897

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

5

Small-scale

0.527

High

186921

TAFA5
Chemokine-like protein TAFA-5

1

0

High-throughput

0.518

High

186924

SPA2L
Spermatogenesis-associated protein 2-like protein

1

0

High-throughput

0.518

High

186938

G6PC3
Glucose-6-phosphatase 3

1

0

High-throughput

0.518

High

186948

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.518

High

186953

NAC2
Sodium/calcium exchanger 2

1

0

High-throughput

0.518

High

186873

K2C8
Keratin, type II cytoskeletal 8

1

1

High-throughput

0.515

High

186900

SC6A3
Sodium-dependent dopamine transporter

1

4

Small-scale

0.515

High

186889

SDC2
Syndecan-2

1

2

High-throughput

0.515

High

186908

PUM1
Pumilio homolog 1

1

1

High-throughput

0.515

High

186910

NR1D2
Nuclear receptor subfamily 1 group D member 2

1

1

High-throughput

0.515

High

186927

MSRB3
Methionine-R-sulfoxide reductase B3

1

0

High-throughput

0.493

High

186946

MITOS
Mitochondrial potassium channel ATP-binding subunit

1

3

High-throughput

0.489

High

140061

SDCB1
Syntenin-1

1

14

Small-scale

0.481

High

186955

GRIP1
Glutamate receptor-interacting protein 1

1

16

Small-scale

0.481

High

186877

HSP7C
Heat shock cognate 71 kDa protein

1

2

Small-scale

0.479

High

186884

DNJB1
DnaJ homolog subfamily B member 1

1

3

Small-scale

0.479

High

186887

DNJA1
DnaJ homolog subfamily A member 1

1

3

Small-scale

0.479

High

186892

BASI
Basigin

1

5

High-throughput

0.479

High

186898

TCPB
T-complex protein 1 subunit beta

1

1

Small-scale

0.479

High

186911

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

186917

RN123
E3 ubiquitin-protein ligase RNF123

1

6

High-throughput

0.479

High

186952

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

Small-scale

0.479

High

186868

FABP7
Fatty acid-binding protein, brain

1

1

High-throughput

0.470

High

186883

TYY1
Transcriptional repressor protein YY1

1

2

High-throughput

0.470

High

186901

CREB5
Cyclic AMP-responsive element-binding protein 5

1

3

High-throughput

0.470

High

186918

TMUB2
Transmembrane and ubiquitin-like domain-containing protein 2

1

4

High-throughput

0.470

High

186880

TCPA
T-complex protein 1 subunit alpha

1

0

Small-scale

0.458

High

186932

PACRG
Parkin coregulated gene protein

1

0

Small-scale

0.458

High

186890

HSP74
Heat shock 70 kDa protein 4

1

3

Small-scale

0.437

High

186909

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

2

0

High-throughput

0.328

High

186925

F219A
Protein FAM219A

2

0

High-throughput

0.328

High

186914

PPM1J
Protein phosphatase 1J

1

0

High-throughput

0.282

High

186928

CCNQ
Cyclin-Q

1

0

High-throughput

0.282

High

186935

TM175
Endosomal/lysosomal proton channel TMEM175

1

0

High-throughput

0.282

High

186937

FUCO2
Plasma alpha-L-fucosidase

1

0

High-throughput

0.282

High

186942

TM231
Transmembrane protein 231

1

0

High-throughput

0.282

High

186882

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

0

High-throughput

0.279

Low

186894

DPOD2
DNA polymerase delta subunit 2

1

0

High-throughput

0.279

Low

186936

CQ080
Mitochondrial nucleoid-associated protein 1

1

0

High-throughput

0.279

Low

186913

FA76B
Protein FAM76B

1

0

High-throughput

0.268

Low

186916

LCE2A
Late cornified envelope protein 2A

1

0

High-throughput

0.268

Low

186920

Q7L8T7
cDNA FLJ40572 fis, clone THYMU2006170

1

0

High-throughput

0.268

Low

186922

Q7Z7K5
HCG1778014

1

0

High-throughput

0.268

Low

186930

SCAM4
Secretory carrier-associated membrane protein 4

1

0

High-throughput

0.268

Low

186939

ZFHX2
Zinc finger homeobox protein 2

1

0

High-throughput

0.268

Low

186929

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025