HitPredict

Interactor 1: BIRC5 (O15392)
Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
Gene: BIRC5

Interactor 2: UBP19 (O94966)
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)
Gene: USP19

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35918893, 37586466
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 1318
+	Hs
		322931 BIRC3_HUMAN (3-96): 8.87e-22: 91.7: 27.66		UBP19_HUMAN (1-1318): 0: 1268: 100.00
+	Hs
		322932 BIRC2_HUMAN (10-88): 1.01e-18: 82.9: 27.85		UBP19_HUMAN (1-1318): 0: 1268: 100.00
+	Hs
		322920 XIAP_HUMAN (11-87): 7.54e-14: 69: 28.57		UBP19_HUMAN (1-1318): 0: 1268: 100.00
+	Hs
		188629 BIRC5_HUMAN (1-142): 2.28e-60: 184: 100.00		UBP2_HUMAN (377-834): 1.97e-77: 270: 20.98
+	Hs
		188728 BIRC5_HUMAN (1-142): 2.28e-60: 184: 100.00		UBP22_HUMAN (479-861): 2.52e-69: 244: 19.64
+	Hs
		288486 BIRC7_HUMAN (7-104): 1.33e-33: 121: 29.59		UBP2_HUMAN (377-834): 1.97e-77: 270: 20.98
+	Hs
		828256 BIRC6_HUMAN (8-88): 8.18e-36: 132: 37.04		UBP8_HUMAN (771-1222): 4.88e-67: 249: 18.12
+	Hs
		1107371 BIRC3_HUMAN (3-96): 8.87e-22: 91.7: 27.66		UBP15_HUMAN (860-1080): 2.24e-17: 90.1: 9.79
+	Hs
		1107511 BIRC2_HUMAN (10-88): 1.01e-18: 82.9: 27.85		UBP15_HUMAN (860-1080): 2.24e-17: 90.1: 9.79
+	Mm
		1222123 XIAP_MOUSE (11-87): 5.98e-14: 69.4: 27.27		UBP15_MOUSE (860-1080): 1.42e-17: 90.9: 10.21
+	Hs
		907377 XIAP_HUMAN (11-87): 7.54e-14: 69: 28.57		UBP11_HUMAN (861-1070): 1.11e-14: 81.7: 7.18