HitPredict

Interactor 1: TMPS2 (O15393)
Transmembrane protease serine 2 (EC 3.4.21.122) (Serine protease 10) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]
Gene: TMPRSS2

Interactor 2: CADH2 (P19022)
Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)
Gene: CDH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	34709727
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 492 Hs			1 906
+	Hs
		618292 TMPS4_HUMAN (117-491): 1.45e-103: 318: 37.21		CADH2_HUMAN (1-906): 0: 911: 100.00
+	Hs
		618268 TM11B_HUMAN (190-489): 7.67e-100: 308: 31.89		CADH2_HUMAN (1-906): 0: 911: 100.00
+	Hs
		188885 TMPS2_HUMAN (1-492): 7.93e-160: 464: 100.00		DSC3_HUMAN (5-899): 0: 699: 30.32
+	Hs
		1037049 TMPS4_HUMAN (117-491): 1.45e-103: 318: 37.21		DSC2_HUMAN (42-899): 0: 709: 30.46
+	Hs
		1037003 TM11B_HUMAN (190-489): 7.67e-100: 308: 31.89		DSC2_HUMAN (42-899): 0: 709: 30.46
+	Hs
		1128557 TMPS4_HUMAN (117-491): 1.45e-103: 318: 37.21		DSC3_HUMAN (5-899): 0: 699: 30.32
+	Hs
		1128526 TM11B_HUMAN (190-489): 7.67e-100: 308: 31.89		DSC3_HUMAN (5-899): 0: 699: 30.32
+	Hs
		437674 HEPS_HUMAN (149-489): 2.39e-96: 298: 32.58		DSG2_HUMAN (153-725): 6.33e-92: 316: 34.54
+	Hs
		1418368 TMPSD_HUMAN (5-488): 1.19e-112: 346: 31.35		PCDBB_HUMAN (438-903): 4.39e-71: 252: 15.65
+	Hs
		1448864 TMPS4_HUMAN (117-491): 1.45e-103: 318: 37.21		PCDGH_HUMAN (390-891): 2.19e-67: 244: 15.91
+	Hs
		1286971 TM11B_HUMAN (190-489): 7.67e-100: 308: 31.89		PCDGH_HUMAN (390-891): 2.19e-67: 244: 15.91