HitPredict

Interactor 1: CSN5 (O35864)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1) (Kip1 C-terminus-interacting protein 2)
Gene: Cops5

Interactor 2: UBC (P0CG50)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]
Gene: UBC

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 334 Mm			1 734
+	Hs
		476142 CSN5_HUMAN (1-334): 4.61e-129: 373: 99.40		UBC_HUMAN (77-724): 0: 790: 97.22
+	Mm
		192886 PSDE_MOUSE (50-332): 3.4e-79: 245: 31.40		UBC_MOUSE (1-734): 0: 912: 100.00
+	Mm
		476691 PSMD7_MOUSE (52-323): 1.21e-57: 190: 15.60		UBC_MOUSE (1-734): 0: 912: 100.00
+	Mm
		476703 BRCC3_MOUSE (56-297): 3.59e-49: 168: 19.05		UBC_MOUSE (1-734): 0: 912: 100.00
+	Rn
		89029 D4AEH3_RAT (52-323): 3.87e-53: 178: 15.25		UBC_RAT (1-724): 0: 898: 97.51
+	Hs
		130705 PSDE_HUMAN (50-332): 3.4e-79: 245: 31.40		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		124740 EIF3F_HUMAN (44-328): 3.64e-65: 211: 14.48		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		176926 EIF3H_HUMAN (52-320): 2.5e-64: 208: 18.57		UBC_HUMAN (77-724): 0: 790: 97.22
+	Hs
		475500 PSMD7_HUMAN (52-323): 1.93e-57: 190: 15.60		UBC_HUMAN (77-724): 0: 790: 97.22
+	At
		1091793 CSN5A_ARATH (1-330): 4.22e-118: 346: 66.17		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	Sc
		477336 RPN11_YEAST (39-332): 1.78e-73: 230: 29.24		UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99
+	Sc
		477501 CSN5_YEAST (22-299): 3.59e-56: 190: 29.51		UBI4P_YEAST (381-724): 5.74e-136: 407: 90.99
+	At
		1092172 PSDE_ARATH (41-332): 2.67e-80: 248: 31.46		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1091965 EIF3H_ARATH (39-314): 1.14e-58: 193: 17.90		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		1091969 PSD7B_ARATH (46-326): 7.54e-55: 183: 15.17		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	At
		188941 PSD7A_ARATH (46-326): 4.18e-55: 183: 14.48		UBQ3_ARATH (457-724): 7.39e-99: 308: 89.55
+	Hs
		130837 PSDE_HUMAN (50-332): 3.4e-79: 245: 31.40		RS27A_HUMAN (609-684): 3.67e-42: 152: 100.00
+	Hs
		130693 PSDE_HUMAN (50-332): 3.4e-79: 245: 31.40		ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69
+	Hs
		130704 PSDE_HUMAN (50-332): 3.4e-79: 245: 31.40		UBB_HUMAN (1-77): 3.45e-27: 112: 98.70
+	Hs
		397853 PSMD7_HUMAN (52-323): 1.93e-57: 190: 15.60		ISG15_HUMAN (228-380): 5.84e-29: 115: 32.69