HitPredict

Interactor 1: KDM6A (O15550)
Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)
Gene: KDM6A

Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37679762
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1401 Hs			1 731
+	Hs
		194598 KDM6A_HUMAN (1-1401): 0: 1667: 100.00		FBXW7_HUMAN (390-730): 3.04e-83: 280: 16.33
+	Hs
		194540 KDM6A_HUMAN (1-1401): 0: 1667: 100.00		WDR5_HUMAN (297-625): 1.46e-64: 219: 16.32
+	Hs
		158690 UTY_HUMAN (1-1393): 0: 1523: 83.49		WDR5_HUMAN (297-625): 1.46e-64: 219: 16.32
+	Hs
		104294 F5H5V6_HUMAN (1-1401): 0: 1458: 75.32		WDR5_HUMAN (297-625): 1.46e-64: 219: 16.32
+	Ce
		1165198 JMJ31_CAEEL (479-1390): 0: 753: 21.52		WDR51_CAEEL (629-731): 1.82e-15: 80.6: 13.59
+	Hs
		185871 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		COP1_HUMAN (1-731): 0: 538: 100.00
+	Dm
		120172 M9PCJ7_DROME (176-523): 2.28e-40: 164: 42.94		WDS_DROME (335-629): 4.71e-64: 219: 16.83
+	Hs
		185575 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		WDR5_HUMAN (297-625): 1.46e-64: 219: 16.32
+	Hs
		1334161 DNJC7_HUMAN (278-509): 2.61e-21: 101: 11.16		POC1A_HUMAN (455-731): 1.85e-68: 232: 22.94
+	Hs
		185787 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		TRAF7_HUMAN (450-730): 2.43e-50: 188: 15.55
+	Hs
		176048 KDM6B_HUMAN (252-871): 4.19e-18: 93.1: 16.07		WDR5_HUMAN (297-625): 1.46e-64: 219: 16.32
+	Ce
		196765 OGT1_CAEEL (98-778): 2.59e-60: 229: 13.06		LIN53_CAEEL (552-730): 5.73e-14: 76.7: 16.75
+	Sp
		238287 CYC8_SCHPO (211-911): 1.6e-37: 155: 12.43		TUP11_SCHPO (5-544): 2.95e-37: 149: 14.00
+	Hs
		718532 CDC27_HUMAN (96-315): 1.8e-11: 71: 23.18		WDR5_HUMAN (297-625): 1.46e-64: 219: 16.32
+	Hs
		185638 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		RBBP4_HUMAN (512-702): 3.24e-20: 96: 14.49
+	Hs
		185738 OGT1_HUMAN (255-640): 7.42e-29: 127: 10.91		RBBP7_HUMAN (476-629): 3.9e-12: 70.9: 29.34
+	Ca
		515424 Q5ADP3_CANAL (276-919): 3.3e-20: 99.7: 12.35		TUP1_CANAL (178-453): 8.51e-13: 73.3: 8.94
+	Hs
		1158952 TTC28_HUMAN (255-558): 2.07e-13: 77.7: 11.33		RBBP7_HUMAN (476-629): 3.9e-12: 70.9: 29.34