HitPredict

Interactor 1: SI1L1 (O43166)
Signal-induced proliferation-associated 1-like protein 1 (SIPA1-like protein 1) (High-risk human papilloma viruses E6 oncoproteins targeted protein 1) (E6-targeted protein 1)
Gene: SIPA1L1

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1804 Hs			1 1088
+	Hs
		1344956 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		196391 SI1L1_HUMAN (1-1804): 0: 1398: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325923 SI1L2_HUMAN (1-1802): 0: 1277: 47.91		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		230279 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		230191 SI1L3_HUMAN (9-1797): 0: 1005: 44.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		681741 TSC2_HUMAN (103-864): 2.82e-172: 572: 14.02		AKT1_HUMAN (532-1043): 2.2e-141: 435: 22.16
+	Hs
		116987 TSC2_HUMAN (103-864): 2.82e-172: 572: 14.02		SGK1_HUMAN (608-1042): 1.07e-131: 408: 28.51
+	Hs
		835063 TSC2_HUMAN (103-864): 2.82e-172: 572: 14.02		KS6A1_HUMAN (519-977): 1.47e-79: 277: 20.34
+	Hs
		1186099 MICA3_HUMAN (1083-1731): 3.09e-13: 77.5: 12.16		AKT3_HUMAN (532-1043): 3.66e-141: 435: 22.01