HitPredict

Interactor 1: HCD2 (O18404)
3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-hydroxysteroid dehydrogenase 10) (17-beta-HSD 10) (EC 1.1.1.51, EC 1.1.1.62) (3-hydroxyacyl-CoA dehydrogenase type II) (Hydroxysteroid dehydrogenase) (EC 1.1.1.-, EC 1.1.1.53) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Scully protein) (Type II HADH)
Gene: scu

Interactor 2: DHB4 (Q9VXJ0)
Peroxisomal multifunctional enzyme type 2 (DmMFE-2) [Includes: (3R)-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.n12); Enoyl-CoA hydratase 2 (EC 4.2.1.119)]
Gene: Mfe2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	adh_short~adh_short
Common GO terms	GO:0003857 - (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 255 Dm			1 598
+	Hs
		1413839 DHRS4_HUMAN (2-251): 1.82e-83: 252: 25.78		DHRS4_HUMAN (1-250): 1.69e-84: 266: 24.06
+	Ss
		1355736 DHRS4_PIG (2-251): 1.29e-80: 245: 24.22		DHRS4_PIG (1-250): 9.48e-81: 257: 22.18
+	Ec
		500300 FABG_ECOLI (2-254): 3.06e-82: 248: 27.45		FABG_ECOLI (8-246): 9.42e-80: 253: 30.80
+	At
		1441464 TRNHA_ARATH (2-251): 1.74e-78: 239: 27.13		TRNHF_ARATH (4-247): 5.64e-81: 257: 24.42
+	At
		1441465 SAG13_ARATH (2-253): 7.97e-78: 237: 24.81		TRNHF_ARATH (4-247): 5.64e-81: 257: 24.42
+	Mm
		1408815 DHRS4_MOUSE (2-251): 3.6e-78: 238: 26.95		DHRS4_MOUSE (1-250): 5.94e-80: 255: 23.68
+	Dm
		1343559 Q8SX57_DROME (2-254): 4.61e-78: 238: 26.52		Q8SX57_DROME (7-245): 5.77e-79: 251: 21.48
+	At
		1492053 SAG13_ARATH (2-253): 7.97e-78: 237: 24.81		SAG13_ARATH (2-247): 3.22e-77: 247: 22.78
+	At
		1492054 SAG13_ARATH (2-253): 7.97e-78: 237: 24.81		TRNHC_ARATH (2-247): 6.17e-77: 247: 21.54
+	Dm
		1343561 Q8SX57_DROME (2-254): 4.61e-78: 238: 26.52		Q9VNF3_DROME (7-245): 3.17e-76: 244: 23.05
+	Mm
		1362242 CBR4_MOUSE (4-254): 2.95e-80: 242: 29.88		CBR4_MOUSE (12-245): 8.11e-74: 237: 26.97
+	At
		1492051 TRNHA_ARATH (2-251): 1.74e-78: 239: 27.13		TRNH9_ARATH (5-255): 1.45e-74: 240: 22.10
+	Dm
		1304688 Q8SX57_DROME (2-254): 4.61e-78: 238: 26.52		Q8IPP8_DROME (8-245): 2.01e-74: 239: 23.14
+	At
		1492052 SAG13_ARATH (2-253): 7.97e-78: 237: 24.81		TRNH9_ARATH (5-255): 1.45e-74: 240: 22.10
+	At
		1492050 SAG13_ARATH (2-253): 7.97e-78: 237: 24.81		TRNH8_ARATH (5-247): 2.19e-74: 239: 22.18
+	Hs
		1326813 CBR4_HUMAN (4-254): 1.67e-79: 240: 29.88		DHB8_HUMAN (3-245): 3.13e-72: 234: 30.35
+	At
		1342066 SAG13_ARATH (2-253): 7.97e-78: 237: 24.81		TRNH2_ARATH (7-247): 8.57e-72: 233: 21.57
+	Hs
		1245786 DHRS4_HUMAN (2-251): 1.82e-83: 252: 25.78		DR4L2_HUMAN (1-195): 1.27e-64: 213: 28.79
+	Mm
		893591 CBR4_MOUSE (4-254): 2.95e-80: 242: 29.88		DHB8_MOUSE (7-244): 9.36e-20: 91.3: 34.52