Interactor 1: PRS8 (O18413)
26S proteasome regulatory subunit 8
Gene: Rpt6

Interactor 2: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.812

The method score is based on:

Property Details
Experiments 22036573, 19079254, 38944040
Identification Methods affinity chromatography technology, two hybrid array, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~PRS7_OB, AAA_lid_3~AAA_lid_3, AAA~Prot_ATP_ID_OB_C, PRS7_OB~Prot_ATP_ID_OB_C
Common GO terms GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005838 - proteasome regulatory particle
GO:0008540 - proteasome regulatory particle, base subcomplex
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 405
Dm

1 433
+ At
+ At
+ Sp
+ At
+ Sp
+ At
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Rn
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm

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Last updated: 11Aug2025