HitPredict

Interactor 1: SRGP3 (O43295)
SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (Mental disorder-associated GAP) (Rho GTPase-activating protein 14) (WAVE-associated Rac GTPase-activating protein) (WRP)
Gene: SRGAP3

Interactor 2: TNFL6 (P48023)
Tumor necrosis factor ligand superfamily member 6 (Apoptosis antigen ligand) (APTL) (CD95 ligand) (CD95-L) (Fas antigen ligand) (Fas ligand) (FasL) (CD antigen CD178) [Cleaved into: Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form (Receptor-binding FasL ectodomain) (Soluble Fas ligand) (sFasL); ADAM10-processed FasL form (APL); FasL intracellular domain (FasL ICD) (SPPL2A-processed FasL form) (SPA)]
Gene: FASLG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19807924
Identification Methods	unspecified method, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1099 Hs			1 281
+	Hs
		815694 SRGP1_HUMAN (1-1087): 0: 708: 67.83		TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00
+	Hs
		253328 SRGP2_HUMAN (1-1087): 0: 675: 57.36		TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00
+	Hs
		815672 RHG04_HUMAN (1-948): 2.35e-172: 532: 43.83		TNFL6_HUMAN (1-281): 1.11e-121: 350: 100.00