Protein: UBC6
Ubiquitin-conjugating enzyme E2 6 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 6) (Ubiquitin carrier protein UBC6) (Ubiquitin-protein ligase UBC6)

Gene: UBC6
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: P33296

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

750579

UBC6
Ubiquitin-conjugating enzyme E2 6

4

17

Small-scale

0.888

High

649480

UBA1
Ubiquitin-activating enzyme E1 1

3

20

Small-scale

0.866

High

750589

RSP5
E3 ubiquitin-protein ligase RSP5

3

20

Small-scale

0.835

High

750597

UBC7
Ubiquitin-conjugating enzyme E2 7

2

16

Small-scale

0.767

High

750592

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

8

20

Small-scale

0.747

High

750595

ASI3
Probable ERAD-associated E3 ubiquitin-protein ligase ASI1

1

3

Small-scale

0.680

High

750596

ASI1
ERAD-associated E3 ubiquitin-protein ligase ASI1

1

3

Small-scale

0.680

High

750587

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

20

Small-scale

0.647

High

750601

HRD1
ERAD-associated E3 ubiquitin-protein ligase HRD1

1

20

Small-scale

0.647

High

750591

IMB4
Importin subunit beta-4

1

3

High-throughput

0.646

High

750584

TUL1
Transmembrane E3 ubiquitin-protein ligase 1

1

5

Small-scale

0.621

High

750593

HUL4
Probable E3 ubiquitin-protein ligase HUL4

1

20

Small-scale

0.621

High

750600

PEX10
Peroxisome biogenesis factor 10

1

20

Small-scale

0.621

High

679527

CDC48
Cell division control protein 48

2

3

Small-scale

0.595

High

750580

XPOT
Exportin-T

1

0

High-throughput

0.578

High

436362

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

20

Small-scale

0.575

High

509469

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

High-throughput

0.575

High

740775

STE14
Protein-S-isoprenylcysteine O-methyltransferase

2

0

Small-scale

0.559

High

392480

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.541

High

376285

YPT1
GTP-binding protein YPT1

1

1

High-throughput

0.536

High

750599

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.536

High

750588

FLC2
Flavin carrier protein 2

1

0

High-throughput

0.518

High

470116

SPS1
Sporulation-specific protein 1

1

5

High-throughput

0.501

High

750594

SC6B2
Protein transport protein SBH2

1

1

Small-scale

0.501

High

750602

GET3
ATPase GET3

1

1

Small-scale

0.501

High

452870

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

High-throughput

0.500

High

453510

PYR1
Multifunctional protein URA2

1

4

High-throughput

0.500

High

486115

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.500

High

750585

KSP1
Serine/threonine-protein kinase KSP1

1

4

High-throughput

0.500

High

750603

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.500

High

431996

ATPF
ATP synthase subunit 4, mitochondrial

1

1

High-throughput

0.489

High

535998

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

1

1

High-throughput

0.489

High

750581

GCN1
eIF-2-alpha kinase activator GCN1

1

6

High-throughput

0.489

High

750583

TCTP
Translationally-controlled tumor protein homolog

1

5

High-throughput

0.489

High

739122

PRP19
Pre-mRNA-processing factor 19

1

9

Small-scale

0.481

High

745254

PEX2
Peroxisomal biogenesis factor 2

1

1

Small-scale

0.481

High

416409

HXKA
Hexokinase-1

1

0

High-throughput

0.479

High

748313

SC61A
Protein transport protein SEC61

1

3

High-throughput

0.479

High

661601

MPCP
Mitochondrial phosphate carrier protein

1

4

High-throughput

0.464

High

721592

RENT1
ATP-dependent helicase NAM7

1

0

Small-scale

0.460

High

613552

ADT2
ADP,ATP carrier protein 2

1

2

High-throughput

0.457

High

750598

TFB3
RNA polymerase II transcription factor B subunit 3

1

1

Small-scale

0.439

High

750586

ARP1
Centractin

1

1

High-throughput

0.417

High

750582

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.279

Low

750590

DPO5
rDNA transcriptional regulator POL5

1

0

High-throughput

0.279

Low

750604

YP229
Uncharacterized protein YPL229W

1

0

High-throughput

0.265

Low

386650

TBB
Tubulin beta chain

1

0

High-throughput

0.261

Low


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Last updated: 11Aug2025