HitPredict

Interactor 1: E41L2 (O43491)
Band 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G)
Gene: EPB41L2

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	17353931, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1005 Hs			1 245
+	Hs
		204644 E41L2_HUMAN (1-1005): 0: 850: 100.00		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		204648 E41L2_HUMAN (1-1005): 0: 850: 100.00		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		204620 E41L2_HUMAN (1-1005): 0: 850: 100.00		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		204621 E41L2_HUMAN (1-1005): 0: 850: 100.00		1433S_HUMAN (1-236): 9.86e-108: 312: 71.85
+	Hs
		204653 E41L2_HUMAN (1-1005): 0: 850: 100.00		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		204643 E41L2_HUMAN (1-1005): 0: 850: 100.00		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		910025 E41L1_HUMAN (119-1005): 0: 582: 43.06		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		647274 E41L1_HUMAN (119-1005): 0: 582: 43.06		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		927524 E41L1_HUMAN (119-1005): 0: 582: 43.06		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		683710 E41L1_HUMAN (119-1005): 0: 582: 43.06		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		982496 E41L1_HUMAN (119-1005): 0: 582: 43.06		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		905110 E41L1_HUMAN (119-1005): 0: 582: 43.06		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33
+	Hs
		663970 PTN4_HUMAN (193-780): 1.5e-149: 469: 28.90		1433E_HUMAN (2-243): 1.31e-144: 406: 63.53
+	Hs
		646653 PTN4_HUMAN (193-780): 1.5e-149: 469: 28.90		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		663973 PTN4_HUMAN (193-780): 1.5e-149: 469: 28.90		1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59
+	Hs
		663962 PTN4_HUMAN (193-780): 1.5e-149: 469: 28.90		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		646848 PTN13_HUMAN (79-990): 4.22e-135: 452: 15.70		1433T_HUMAN (1-245): 9.47e-142: 398: 100.00
+	Hs
		683305 PTN13_HUMAN (79-990): 4.22e-135: 452: 15.70		1433B_HUMAN (1-242): 5.01e-139: 391: 81.82
+	Hs
		663976 PTN4_HUMAN (193-780): 1.5e-149: 469: 28.90		1433F_HUMAN (2-242): 7.16e-106: 307: 71.43
+	Hs
		663969 PTN4_HUMAN (193-780): 1.5e-149: 469: 28.90		1433G_HUMAN (1-242): 5.48e-105: 305: 70.33