HitPredict

Interactor 1: RNF13 (O43567)
E3 ubiquitin-protein ligase RNF13 (EC 2.3.2.27) (RING finger protein 13)
Gene: RNF13

Interactor 2: AP3S1 (Q92572)
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)
Gene: AP3S1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	26186194, 28514442, 33961781, 34831286
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 381 Hs			1 193
+	Hs
		207550 RNF13_HUMAN (1-381): 6.93e-114: 338: 100.00		AP3S2_HUMAN (1-192): 1.95e-71: 216: 84.38
+	Hs
		207549 RNF13_HUMAN (1-381): 6.93e-114: 338: 100.00		AP1S2_HUMAN (2-158): 5.07e-50: 160: 35.03
+	Hs
		1267489 RN167_HUMAN (15-330): 2.04e-82: 257: 49.54		AP3S1_HUMAN (1-193): 7.1e-75: 224: 100.00
+	Hs
		880422 RN149_HUMAN (43-319): 4.7e-58: 196: 22.85		AP1S2_HUMAN (2-158): 5.07e-50: 160: 35.03